Chemokine receptors, CCR4 and CXCR3, found on T cells, are implicated in the
inflammatory response in the skin, joint and lymph nodes (LNs), but whether they mediate T …

CCR4 and CXCR3 are expressed on several T‐cell subsets in inflamed tissues, yet their
role in tissue‐specific recruitment is unclear. We examined the contributions of CCR4 and …

Lymphocytes in inflamed tissues express numerous chemokine receptors. The relative
importance of these receptors for migration in inflammation is unclear. The role of CXCR3 in …

T cell recirculation through extralymphoid tissues is essential to immune surveillance, host
defense and inflammation. In this process, T cells enter the tissue from the blood and …

Naïve T cells, when activated by specific antigen and cytokines, up-regulate adhesion
molecules as well as chemokine receptors on their surface, which allows them to migrate to …

The chemokine receptors are seven transmembrane, G-protein-coupled surface receptors
that play key roles in the migration and localization of leukocytes to the skin during …

CCR6 is expressed in a number of dermatological inflammatory diseases. Here, we report
that mice sensitized with the hapten oxazolone had increased numbers of CCR6+ T cells in …

Inflamed skin contains CD4 T-cell subsets that express chemokine receptors CCR4, CCR6,
and/or CCR10. Prior attempts to reveal the distinct role (s) of each receptor in T-cell …

Chemokine-directed leukocyte migration is essential for immune and inflammatory
responses. The chemokine receptor CCR7, by responding to chemokines CCL19 and …

We were unable to identify cell surface CCR8 with the rat anti-CCR8 Ab that they have used
(Fig. 1A). This was precisely the reason why we have generated our own anti-CCR8 Ab …