SORTING NEXIN1 Is Required for Modulating the Trafficking and Stability of the Arabidopsis IRON-REGULATED TRANSPORTER1

R Ivanov, T Brumbarova, A Blum, AM Jantke… - The Plant …, 2014 - academic.oup.com
Dicotyledonous plants growing under limited iron availability initiate a response resulting in
the solubilization, reduction, and uptake of soil iron. The protein factors responsible for these …

Hormone influence on the spatial regulation of IRT1 expression in iron-deficient Arabidopsis thaliana roots

A Blum, T Brumbarova, P Bauer… - Plant signaling & …, 2014 - Taylor & Francis
The IRON-REGULATED TRANSPORTER1 (IRT1) is the principal importer of soil iron in
Arabidopsis thaliana. It has a complex intracellular trafficking behavior, including continuous …

Iron-induced turnover of the Arabidopsis IRON-REGULATED TRANSPORTER1 metal transporter requires lysine residues

L Kerkeb, I Mukherjee, I Chatterjee, B Lahner… - Plant …, 2008 - academic.oup.com
Iron is an essential micronutrient but is toxic if accumulated at high levels. Thus, iron uptake
and distribution in plants are controlled by precise regulatory mechanisms. IRON …

[HTML][HTML] AtIREG2 encodes a tonoplast transport protein involved in iron-dependent nickel detoxification in Arabidopsis thaliana roots

G Schaaf, A Honsbein, AR Meda, S Kirchner… - Journal of Biological …, 2006 - ASBMB
Iron acquisition in Arabidopsis depends mainly on AtIRT1, a Fe 2+ transporter in the plasma
membrane of root cells. However, substrate specificity of AtIRT1 is low, leading to an excess …

The Ferroportin Metal Efflux Proteins Function in Iron and Cobalt Homeostasis in Arabidopsis

J Morrissey, IR Baxter, J Lee, L Li, B Lahner… - The Plant …, 2009 - academic.oup.com
Relatively little is known about how metals such as iron are effluxed from cells, a necessary
step for transport from the root to the shoot. Ferroportin (FPN) is the sole iron efflux …

Root‐to‐shoot iron partitioning in Arabidopsis requires IRON‐REGULATED TRANSPORTER1 (IRT1) protein but not its iron (II) transport function

J Quintana, M Bernal, M Scholle… - The Plant …, 2022 - Wiley Online Library
SUMMARY IRON‐REGULATED TRANSPORTER1 (IRT1) is the root high‐affinity ferrous
iron (Fe) uptake system and indispensable for the completion of the life cycle of Arabidopsis …

Monoubiquitin-dependent endocytosis of the iron-regulated transporter 1 (IRT1) transporter controls iron uptake in plants

M Barberon, E Zelazny, S Robert… - Proceedings of the …, 2011 - National Acad Sciences
Plants take up iron from the soil using the IRON-REGULATED TRANSPORTER 1 (IRT1)
high-affinity iron transporter at the root surface. Sophisticated regulatory mechanisms allow …

AtIRT1, the Primary Iron Uptake Transporter in the Root, Mediates Excess Nickel Accumulation in Arabidopsis thaliana

S Nishida, C Tsuzuki, A Kato, A Aisu… - Plant and Cell …, 2011 - academic.oup.com
Nickel (Ni) is an essential nutrient for plants, but excessive amounts can be toxic. Ni
competes with iron (Fe) in vivo, raising the possibility that Ni is competitively taken up via the …

Iron-nicotianamine transporters are required for proper long distance iron signaling

RK Kumar, HH Chu, C Abundis, K Vasques… - Plant …, 2017 - academic.oup.com
The mechanisms of root iron uptake and the transcriptional networks that control root-level
regulation of iron uptake have been well studied, but the mechanisms by which shoots …

Polarization of IRON-REGULATED TRANSPORTER 1 (IRT1) to the plant-soil interface plays crucial role in metal homeostasis

M Barberon, G Dubeaux, C Kolb… - Proceedings of the …, 2014 - National Acad Sciences
In plants, the controlled absorption of soil nutrients by root epidermal cells is critical for
growth and development. IRON-REGULATED TRANSPORTER 1 (IRT1) is the main root …