Minimum conditions for the induction of cortical spreading depression in brain slices

YT Tang, JM Mendez, JJ Theriot… - Journal of …, 2014 - journals.physiology.org
Cortical spreading depression (CSD) occurs during various forms of brain injury such as
stroke, subarachnoid hemorrhage, and brain trauma, but it is also thought to be the …

Spreading depression: imaging and blockade in the rat neocortical brain slice

TR Anderson, RD Andrew - Journal of neurophysiology, 2002 - journals.physiology.org
Spreading depression (SD) is a profound but transient depolarization of neurons and glia
that migrates across the cortical and subcortical gray at 2–5 mm/min. Under normoxic …

[HTML][HTML] Increased calcium influx triggers and accelerates cortical spreading depression in vivo in male adult rats

D Torrente, RF Mendes-da-Silva, AAC Lopes… - Neuroscience …, 2014 - Elsevier
Cortical spreading depression (CSD) is a depolarization wave associated with neurological
disorders such as migraine, cerebral ischemia and traumatic brain injury. The mechanism of …

Anesthetic effects on susceptibility to cortical spreading depression

C Kudo, M Toyama, A Boku, H Hanamoto… - …, 2013 - Elsevier
Cortical spreading depression (CSD) is a transient neuronal and glial depolarization and
disruption of membrane ionic gradients that propagates slowly across the cerebral cortex …

Clinical relevance of cortical spreading depression in neurological disorders: migraine, malignant stroke, subarachnoid and intracranial hemorrhage, and traumatic …

M Lauritzen, JP Dreier, M Fabricius… - Journal of Cerebral …, 2011 - journals.sagepub.com
Cortical spreading depression (CSD) and depolarization waves are associated with
dramatic failure of brain ion homeostasis, efflux of excitatory amino acids from nerve cells …

High extracellular potassium, and not extracellular glutamate, is required for the propagation of spreading depression

TP Obrenovitch, E Zilkha - Journal of neurophysiology, 1995 - journals.physiology.org
1. Cortical spreading depression (SD) is a propagating transient suppression of electrical
activity associated with depolarization, which may contribute to the pathophysiology of …

Mechanisms of neuronal silencing after cortical spreading depression

PM Sawant-Pokam, P Suryavanshi, JM Mendez… - Cerebral …, 2016 - academic.oup.com
Cortical spreading depression (CSD) is associated with migraine, stroke, and traumatic
brain injury, but its mechanisms remain poorly understood. One of the major features of CSD …

Spreading depression in the brainstem of the adult rat: electrophysiological parameters and influences on regional brainstem blood flow

F Richter, R Bauer, A Lehmenkühler… - Journal of Cerebral …, 2008 - journals.sagepub.com
Cortical spreading depression is a pathophysiological excitation wave that occurs during
pathophysiological brain conditions such as ischemic brain infarction, migraine aura, and …

Is there a correlation between spreading depression, neurogenic inflammation, and nociception that might cause migraine headache?

A Ebersberger, HG Schaible… - Annals of Neurology …, 2001 - Wiley Online Library
The time course of propagation of scotoma and blood flow changes during migraine aura
parallels the phenomenon of cortical spreading depression (CSD). It was proposed that …

Cortical spreading depression and migraine

AC Charles, SM Baca - Nature Reviews Neurology, 2013 - nature.com
Cortical spreading depression (CSD), a slowly propagated wave of depolarization followed
by suppression of brain activity, is a remarkably complex event that involves dramatic …