Dengue virus (DENV) represents a major threat to public health worldwide. Early DENV
diagnosis should not only detect the infection but also identify patients with a higher …

Dengue is a worldwide problem characterized by a multifactorial pathogenesis. Considering
the viral components, it is known that high viremia or high levels of the secreted …

Dengue diagnosis primarily relies on NS1 ELISA and serological (IgG/IgM) tests. There are
reports of low and variable sensitivity of the widely used NS1 ELISA tests. Poor sensitivity …

In 2010, a large outbreak of dengue occurred in Santos, Brazil. The detection of the NS1
antigen was used for diagnosis in addition to the detection of IgG, IgM, and RNA. A large …

Background We compared the performance of two new commercial tests for the detection of
dengue NS1 protein during the clinical phase of dengue virus (DENV) infection—an …

Background Dengue virus (DENV) infections pose one of the largest global barriers to
human health. The four serotypes (DENV 1–4) present different symptoms and influence …

The fact that the diagnosis of infection with dengue virus is usually made by detecting IgM
antibodies during the convalescent phase of the disease interferes with disease …

Background Currently, no dengue NS1 detection kit has regulatory approval for the
diagnosis of acute dengue fever. Here we report the sensitivity and specificity of the InBios …

Background Non-structural protein 1 (NS1) of dengue virus circulates in the serum of
patients during the acute phase of the disease. Objectives To determine whether NS1 …

Background Early detection of complications significantly reduces dengue associated
mortality and morbidity. We set out to determine if the NS1 rapid antigen detection test could …