In the pre-vaccine era, there was little information about clinical pertussis in adults, although
deaths were noted. Today Bordetella pertussis infection in adults is noted to cause a full …

Pertussis is an epidemic disease caused by Bordetella pertussis and also to a lesser extent
by Bordetella parapertussis. Classical illness lasts 4–8 weeks and is characterized by …

Pertussis is an acute respiratory tract infection charac-terized by severe coughing spasms
that may end with an inspiratory whoop. The Chinese name for this illness,“the 100-day …

The introduction of routine vaccination against Bordetella pertussis more than a half century
ago led to a drastic decline in the number of reported cases of pertussis. It was originally …

Pertussis was first recognized as an epidemic disease in the 16th century. The classic
illness is a three-stage illness (catarrhal, spasmodic, and convalescent), with a distinctive …

Transmission of pertussis among adults is being increasingly recognized. About 1 or 2 in
1,000 adolescents and adults develop pertussis each year,⩾ 12% of persons with acute …

In the prevaccine era pertussis epidemics followed a cyclic pattern, with peaks every 2 to 5
years. With the marked reduction of pertussis by vaccination, the same cyclic pattern still …

Before vaccination, pertussis was a universal disease of early childhood. Although apparent
control of the disease in the United States and other countries was achieved through …

Background Resurgence of pertussis in the post-vaccination era has been reported in
Western countries. A shift of cases from school-age children to adolescents, adults and …

Pertussis or whooping cough, caused by Bordetella pertussis, is a severe respiratory
disease that can be fatal in young infants. Two types of vaccines are available and widely …