Pathological alteration of TDP-43 (TAR DNA-binding protein-43), a protein involved in
various RNA-mediated processes, is a hallmark feature of the neurodegenerative diseases …

Aggregation of TAR DNA-binding protein of 43 kDa (TDP-43) is a pathological signature of
amyotrophic lateral sclerosis (ALS). Although accumulating evidence suggests the …

Accumulating evidence suggests that pathogenic TAR DNA-binding protein (TDP)-43
fragments contain a partial RNA-recognition motif domain 2 (RRM2) in amyotrophic lateral …

Abstract TDP-43 (TAR DNA binding protein of 43kDa) and its C-terminal fragments are
thought to be linked to the pathologies of amyotrophic lateral sclerosis and frontotemporal …

Aggregates of the RNA-binding protein TDP-43 (TAR DNA-binding protein) are a hallmark of
the overlapping neurodegenerative disorders amyotrophic lateral sclerosis (ALS) and …

The TAR DNA-binding protein 43 (TDP-43) is a nucleic acid-binding protein implicated in
gene regulation and RNA processing and shuffling. It is a ribonuclear protein that carries out …

TDP-43 is the major pathological protein identified in the cellular inclusions in amyotrophic
lateral sclerosis and frontotemporal lobar degeneration. The pathogenic forms of TDP-43 …

Aggregation of TAR DNA binding protein-43 (TDP-43) is a hallmark feature of amyotrophic
lateral sclerosis and frontotemporal lobar degeneration. Under pathogenic conditions …

TDP-43 (TAR DNA-binding protein 43) is an hnRNP (heterogeneous nuclear
ribonucleoprotein) protein whose role in cellular processes has come to the forefront of …

Transactivation response element (TAR) DNA-binding protein 43 (TDP-43) is the principal
component of ubiquitinated inclusions characteristic of most forms of amyotrophic lateral …