Deficits in discrimination after experimental frontal brain injury are mediated by motivation and can be improved by nicotinamide administration

C Vonder Haar, WR Maass, EA Jacobs… - Journal of …, 2014 - liebertpub.com
One of the largest challenges in experimental neurotrauma work is the development of
models relevant to the human condition. This includes both creating similar pathophysiology …

Simple tone discriminations are disrupted following experimental frontal traumatic brain injury in rats

C Vonder Haar, TR Smith, EJ French, KM Martens… - Brain injury, 2014 - Taylor & Francis
Primary objective: To assess cognitive deficits in a rat model of brain injury. Research
design: Cognitive deficits are some of the most pervasive and enduring symptoms of frontal …

A discrimination task used as a novel method of testing decision-making behavior following traumatic brain injury

KM Martens, C Vonder Haar, BA Hutsell… - Journal of …, 2012 - liebertpub.com
Traumatic brain injury (TBI) results in a multitude of deficits following injury. Some of the
most pervasive in humans are the changes that affect frontally-mediated cognitive …

Motor and cognitive function evaluation following experimental traumatic brain injury

ST Fujimoto, L Longhi, KE Saatman… - … & biobehavioral reviews, 2004 - Elsevier
Traumatic brain injury (TBI) in humans may cause extensive sensorimotor and cognitive
dysfunction. As a result, many TBI researchers are beginning to assess behavioral …

Longitudinal characterization of motor and cognitive deficits in a model of penetrating ballistic-like brain injury

DA Shear, XCM Lu, MC Bombard… - Journal of …, 2010 - liebertpub.com
Traumatic brain injury (TBI) produces a wide range of motor and cognitive changes. While
some neurological symptoms may respond to therapeutic intervention during the initial …

A hierarchy of neurobehavioral tasks discriminates between mild and moderate brain injury in rats

SGA Baki, HY Kao, E Kelemen, AA Fenton, PJ Bergold - Brain research, 2009 - Elsevier
Behavioral analysis commonly assesses cognitive deficits in rodents following traumatic
brain injury (TBI). We examined rats that received sham, mild or moderate injury in the …

Detecting behavioral deficits in rats after traumatic brain injury

N Hausser, K Johnson, MA Parsley, J Guptarak… - JoVE (Journal of …, 2018 - jove.com
With the increasing incidence of traumatic brain injury (TBI) in both civilian and military
populations, TBI is now considered a chronic disease; however, few studies have …

The effect of injury severity on behavior: a phenotypic study of cognitive and emotional deficits after mild, moderate, and severe controlled cortical impact injury in mice

PM Washington, PA Forcelli, T Wilkins… - Journal of …, 2012 - liebertpub.com
Traumatic brain injury (TBI) can cause a broad array of behavioral problems including
cognitive and emotional deficits. Human studies comparing neurobehavioral outcomes after …

A comparison of two cognitive test paradigms in a penetrating brain injury model

AR Davis, DA Shear, Z Chen, XCM Lu… - Journal of neuroscience …, 2010 - Elsevier
A rat model of penetrating ballistic-like brain injury (PBBI) was recently established to study
military-relevant severe traumatic brain injury (TBI). The purpose of this study was to conduct …

Dissociable long-term cognitive deficits after frontal versus sensorimotor cortical contusions

MD Lindner, MA Plone, CK Cain, B Frydel… - Journal of …, 1998 - liebertpub.com
Cognitive deficits are the most enduring and disabling sequelae of human traumatic brain
injury (TBI), but quantifying the magnitude, duration, and pattern of cognitive deficits …