Deficits in discrimination after experimental frontal brain injury are mediated by motivation and can be improved by nicotinamide administration
C Vonder Haar, WR Maass, EA Jacobs… - Journal of …, 2014 - liebertpub.com
One of the largest challenges in experimental neurotrauma work is the development of
models relevant to the human condition. This includes both creating similar pathophysiology …
models relevant to the human condition. This includes both creating similar pathophysiology …
Simple tone discriminations are disrupted following experimental frontal traumatic brain injury in rats
Primary objective: To assess cognitive deficits in a rat model of brain injury. Research
design: Cognitive deficits are some of the most pervasive and enduring symptoms of frontal …
design: Cognitive deficits are some of the most pervasive and enduring symptoms of frontal …
A discrimination task used as a novel method of testing decision-making behavior following traumatic brain injury
Traumatic brain injury (TBI) results in a multitude of deficits following injury. Some of the
most pervasive in humans are the changes that affect frontally-mediated cognitive …
most pervasive in humans are the changes that affect frontally-mediated cognitive …
Motor and cognitive function evaluation following experimental traumatic brain injury
ST Fujimoto, L Longhi, KE Saatman… - … & biobehavioral reviews, 2004 - Elsevier
Traumatic brain injury (TBI) in humans may cause extensive sensorimotor and cognitive
dysfunction. As a result, many TBI researchers are beginning to assess behavioral …
dysfunction. As a result, many TBI researchers are beginning to assess behavioral …
Longitudinal characterization of motor and cognitive deficits in a model of penetrating ballistic-like brain injury
DA Shear, XCM Lu, MC Bombard… - Journal of …, 2010 - liebertpub.com
Traumatic brain injury (TBI) produces a wide range of motor and cognitive changes. While
some neurological symptoms may respond to therapeutic intervention during the initial …
some neurological symptoms may respond to therapeutic intervention during the initial …
A hierarchy of neurobehavioral tasks discriminates between mild and moderate brain injury in rats
Behavioral analysis commonly assesses cognitive deficits in rodents following traumatic
brain injury (TBI). We examined rats that received sham, mild or moderate injury in the …
brain injury (TBI). We examined rats that received sham, mild or moderate injury in the …
Detecting behavioral deficits in rats after traumatic brain injury
N Hausser, K Johnson, MA Parsley, J Guptarak… - JoVE (Journal of …, 2018 - jove.com
With the increasing incidence of traumatic brain injury (TBI) in both civilian and military
populations, TBI is now considered a chronic disease; however, few studies have …
populations, TBI is now considered a chronic disease; however, few studies have …
The effect of injury severity on behavior: a phenotypic study of cognitive and emotional deficits after mild, moderate, and severe controlled cortical impact injury in mice
PM Washington, PA Forcelli, T Wilkins… - Journal of …, 2012 - liebertpub.com
Traumatic brain injury (TBI) can cause a broad array of behavioral problems including
cognitive and emotional deficits. Human studies comparing neurobehavioral outcomes after …
cognitive and emotional deficits. Human studies comparing neurobehavioral outcomes after …
A comparison of two cognitive test paradigms in a penetrating brain injury model
AR Davis, DA Shear, Z Chen, XCM Lu… - Journal of neuroscience …, 2010 - Elsevier
A rat model of penetrating ballistic-like brain injury (PBBI) was recently established to study
military-relevant severe traumatic brain injury (TBI). The purpose of this study was to conduct …
military-relevant severe traumatic brain injury (TBI). The purpose of this study was to conduct …
Dissociable long-term cognitive deficits after frontal versus sensorimotor cortical contusions
MD Lindner, MA Plone, CK Cain, B Frydel… - Journal of …, 1998 - liebertpub.com
Cognitive deficits are the most enduring and disabling sequelae of human traumatic brain
injury (TBI), but quantifying the magnitude, duration, and pattern of cognitive deficits …
injury (TBI), but quantifying the magnitude, duration, and pattern of cognitive deficits …