Introduction: Spinal cord injury (SCI) occurs within seconds, but host responses may take
years. Although life expectancy has increased, half of the survivors end up as paraplegics …

The prospects for successful clinical trials of neuroprotective and neurorestorative
interventions for patients with acute and chronic myelopathies depend on preclinical animal …

Spinal cord injury (SCI) often causes loss of sensory and motor function resulting in a
significant reduction in quality of life for patients. Currently, no therapies are available that …

There is no choice other than rehabilitation as a practical medical treatment to restore
impairments or improve activities after acute treatment in people with spinal cord injury …

Traumatic spinal cord injuries (SCIs) continue to be a major healthcare concern, with a rising
prevalence worldwide. In response to this growing medical challenge, considerable …

Spinal cord trauma activates the immune system and elicits leukocyte recruitment to the site
of injury. This increase in immunological activity contributes to acute lesion expansion over a …

Severe spinal cord injury (SCI) leads to devastating loss of neurological function below the
level of injury and adversely affects multiple body systems. Most basic research on SCI is …

The journey toward a cure for spinal cord injury (SCI) has taken many paths. In this article,
we review these paths, and highlight the clinical applications of these experimental repair …

Over the past three decades, multiple mechanisms limiting central nervous system
regeneration have been identified. Here, we address plasticity arising from spared systems …

Spinal cord injuries devastate the lives of those affected. Normally, acute injury leads to
chronic injury in the spinal cord, although this has a variable impact on normal sensory and …