Significance: Blood forming, hematopoietic stem cells (HSCs) mostly reside in the bone
marrow in a quiescent, nonmotile state via adhesion interactions with stromal cells and …

Oxidative stress is related to ageing and degenerative diseases, including cancer. However,
a moderate amount of reactive oxygen species (ROS) is required for the regulation of …

Hematopoietic stem cells (HSCs) are responsible for sustaining hematopoietic homeostasis
and regeneration after injury for the entire lifespan of an organism through self-renewal …

Bone marrow (BM)-derived stem and progenitor cell functions including self-renewal,
differentiation, survival, migration, proliferation, and mobilization are regulated by unique …

Reactive oxygen species (ROS), previously considered toxic by-products of aerobic
metabolism, are increasingly recognized as regulators of cellular signaling. Keeping ROS …

Hematopoietic stem cells (HSCs) are defined by their ability both to self-renew and to give
rise to fresh blood cells throughout the lifetime of an animal. The failure of HSCs to self …

Significance: Reactive oxygen species (ROS), byproducts of aerobic metabolism, are
increased in many types of cancer cells. Increased endogenous ROS lead to adaptive …

Reactive oxygen species (ROS) are a heterogeneous group of molecules that are generated
by mature myeloid cells during innate immune responses, and are also implicated in normal …

Reactive oxygen species (ROS) and ROS‐dependent (redox regulation) signaling pathways
and transcriptional activities are thought to be critical in stem cell self‐renewal and …

Stem cells are characterized by their unique ability of self-renewal to maintain the so-called
stem cell pool. Over the past decades, reactive oxygen species (ROS) have been …