Oxidative stress is a common hallmark of neuronal cell death associated with
neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, as well as …

THE GENERATION of reactive oxygen species (ROS) and re-active nitrogen species (RNS)
leads to oxidative or nitrosative damage or both to cellular proteins, lipids, and DNA (a …

The brain is vulnerable to excessive oxidative insults because of its abundant lipid content,
high energy requirements, and weak antioxidant capacity. Reactive oxygen species (ROS) …

Oxidative stress, in which production of highly reactive oxygen species (ROS) and reactive
nitrogen species (RNS) overwhelms antioxidant defenses, is a feature of many neurological …

Oxidative stress and mitochondrial dysfunction are important features present in Alzheimer's
disease (AD). They appear early and contribute to disease progression, both in human …

Cellular redox state has been increasingly recognized as a critical component of stress-
induced cellular responses and disease. Inherent in these responses are reactive oxygen …

Oxidative stress in the central nervous system is strongly associated with neuronal cell death
in the pathogenesis of several neurodegenerative diseases such as Alzheimer′ s disease …

Antioxidants are a class of molecules with an innate affinity to neutralize reactive oxygen
species (ROS), which are known to cause oxidative stress. Oxidative stress has been …

There is widespread recognition that reactive oxygen species (ROS) play key roles in
normal brain function and pathology in the context of neurological disease. Oxidative stress …

Neurological disorders include a variety of conditions, including Alzheimer's disease, motor
neuron disease and Parkinson's disease, affecting longevity and quality of life, and their …