The physiological and pathophysiological functions of renal and extrarenal vasopressin V2 receptors

KV Juul, DG Bichet, S Nielsen… - American journal of …, 2014 - journals.physiology.org
The arginine vasopressin (AVP) type 2 receptor (V2R) is unique among AVP receptor
subtypes in signaling through cAMP. Its key function is in the kidneys, facilitating the urine …

Cellular and subcellular distribution of the type-2 vasopressin receptor in the kidney

RA Fenton, L Brønd, S Nielsen… - American Journal of …, 2007 - journals.physiology.org
Arginine vasopressin (AVP) is essential for maintaining body fluid homeostasis. The
antidiuretic effects of AVP are initialized by binding of AVP to the type-2 vasopressin …

Vasopressin V1a and V1b receptors: from molecules to physiological systems

T Koshimizu, K Nakamura, N Egashira… - Physiological …, 2012 - journals.physiology.org
The neurohypophysial hormone arginine vasopressin (AVP) is essential for a wide range of
physiological functions, including water reabsorption, cardiovascular homeostasis, hormone …

Sex differences in vasopressin V2 receptor expression and vasopressin-induced antidiuresis

J Liu, N Sharma, W Zheng, H Ji… - American Journal …, 2011 - journals.physiology.org
The renal vasopressin V2 receptor (V2R) plays a critical role in physiological and
pathophysiological processes associated with arginine vasopressin (AVP)-induced …

Localization of the vasopressin V1a and V2 receptors within the renal cortical and medullary circulation

F Park, DL Mattson, MM Skelton… - American Journal of …, 1997 - journals.physiology.org
Arginine vasopressin (AVP) is a potent vasoconstrictor that preferentially reduces renal
medullary blood flow through the stimulation of the vasopressin V1a receptor (V1aR) …

Vasopressin increases urinary acidification via V1a receptors in collecting duct intercalated cells

T Giesecke, N Himmerkus, J Leipziger… - Journal of the …, 2019 - journals.lww.com
Background Antagonists of the V1a vasopressin receptor (V1aR) are emerging as a strategy
for slowing progression of CKD. Physiologically, V1aR signaling has been linked with acid …

Renal tubular vasopressin receptors downregulated by dehydration

M Steiner, MI Phillips - American Journal of Physiology-Cell …, 1988 - journals.physiology.org
Receptors for arginine vasopressin (AVP) were characterized in tubular epithelial
basolateral membranes (BL membranes) prepared from the kidneys of male Sprague …

Regulation of the vasopressin V2 receptor by vasopressin in polarized renal collecting duct cells

JH Robben, N Knoers, PMT Deen - Molecular biology of the cell, 2004 - Am Soc Cell Biol
Binding of arginine-vasopressin (AVP) to its V2 receptor (V2R) in the basolateral membrane
of principal cells induces Aquaporin-2–mediated water reabsorption in the kidney. To study …

Therapeutic potential of vasopressin receptor antagonists

F Ali, M Guglin, P Vaitkevicius, JK Ghali - Drugs, 2007 - Springer
Arginine vasopressin (AVP) is a neuropeptide hormone that plays an important role in
circulatory and sodium homeostasis, and regulating serum osmolality. Several clinical …

[HTML][HTML] Vasopressin regulation of blood pressure and volume: findings from V1a receptor–deficient mice

T Aoyagi, T Koshimizu, A Tanoue - Kidney international, 2009 - Elsevier
[Arg 8]-vasopressin (AVP) has several functions via its three distinct receptors, V1a, V1b,
and V2. The V1a vasopressin receptor (V1aR) is expressed in blood vessels and involved in …