Altered nociception in mice with genetically induced hypoglutamatergic tone
V Kayser, F Viguier, M Melfort, S Bourgoin, M Hamon… - Neuroscience, 2015 - Elsevier
Extensive pharmacological evidence supports the idea that glutamate plays a key role in
both acute and chronic pain. In the present study, we investigated the implication of the …
both acute and chronic pain. In the present study, we investigated the implication of the …
氟比洛芬酯在髋部骨折模型大鼠损伤控制中的作用: 降低机体炎症反应
韩亚军， 帖小佳， 侯彦杰， 郭洪亮， 王治洲， 王莲朋 - 中国组织工程研究, 2015 - cjter.com
背景: 自从损伤控制理论体系建立以来, 这一理论逐渐在骨科领域中应用, 特别是在老年髋部骨折
的修复治疗中, 减轻了炎症反应的负作用. 目的: 在损伤控制理论的基础上, 探讨应用氟比洛芬酯 …
的修复治疗中, 减轻了炎症反应的负作用. 目的: 在损伤控制理论的基础上, 探讨应用氟比洛芬酯 …
Brain kinin B1 receptor is upregulated by the oxidative stress and its activation leads to stereotypic nociceptive behavior in insulin-resistant rats
JP Dias, HDB Gariépy, B Ongali, R Couture - Peptides, 2015 - Elsevier
Abstract Kinin B1 receptor (B1R) is virtually absent under physiological condition, yet it is
highly expressed in models of diabetes mellitus. This study aims at determining:(1) whether …
highly expressed in models of diabetes mellitus. This study aims at determining:(1) whether …
Lipid kinases as therapeutic targets for chronic pain
Existing analgesics are not efficacious in treating all patients with chronic pain and have
harmful side effects when used long term. A deeper understanding of pain signaling and …
harmful side effects when used long term. A deeper understanding of pain signaling and …
In the pubertal rat, the regulation of ovarian function involves the synergic participation of the sensory and sympathetic innervations that arrive at the gonad
L Morales-Ledesma, A Trujillo, J Apolonio - Reproductive Biology and …, 2015 - Springer
Background The present study investigates sectioning the superior ovarian nerve (SON) in
rats with functional sensorial denervation induced by capsaicin administration at birth and …
rats with functional sensorial denervation induced by capsaicin administration at birth and …
GABAA-benzodiazepine receptors in the dorsomedial (Dm) telencephalon modulate restraint-induced antinociception in the fish Leporinus macrocephalus
The possibility that fish experience pain has been denied based on the absence of the
neural substrates to support this “experience”. In this context, the identification of brain …
neural substrates to support this “experience”. In this context, the identification of brain …
Temperature differentially facilitates spontaneous but not evoked glutamate release from cranial visceral primary afferents
JA Fawley, ME Hofmann, TM Largent-Milnes… - PloS one, 2015 - journals.plos.org
Temperature is fundamentally important to all biological functions including synaptic
glutamate release. Vagal afferents from the solitary tract (ST) synapse on second order …
glutamate release. Vagal afferents from the solitary tract (ST) synapse on second order …
[PDF][PDF] Pharmacological evaluation of stem bark of Callicarpa arborea Roxb
MH Shihan, Z Al Mahmud, N Qais… - Dhaka University Journal …, 2015 - academia.edu
The ethanol extract of stem bark of Callicarpa arborea and its different fractions were
investigated for various pharmacological properties. In the acetic acid-induced writhing …
investigated for various pharmacological properties. In the acetic acid-induced writhing …
Antinociceptive and Anti-inflammatory Activities of the Methanolic Extract from the Stem Bark of Lophanthera lactescens
GCM dos Santos, RD Fernandes, TR Barros… - Planta …, 2015 - thieme-connect.com
Lophanthera lactescens is a medicinal plant commonly used in traditional medicine to
relieve fever and pain in inflammatory processes. In the present study, the in vivo …
relieve fever and pain in inflammatory processes. In the present study, the in vivo …