Purine Riboswitches: A model system for the study of RNA structural biology and a platform for the advancement of synthetic RNA technologies

JG Marcano-Velázquez - 2015 - search.proquest.com
The scientific discipline known as synthetic biology aims to develop a set of tools and
engineering principles to design artificial biological systems for the production of commodity …

Evaluation and characterisation of phenotypic heterogeneity in Chinese Hamster Ovary cell populations during long-term culture

A Fernandez Martell - 2015 - etheses.whiterose.ac.uk
The selection of CHO cell lines for manufacturing therapeutic proteins involves multiple
screening steps of transfected cells that would meet industrial standards such as productivity …

[图书][B] Development of artificial viruses for nanomedicine and gene therapy

P Saccardo - 2015 - ddd.uab.cat
The convergence of different field as biotechnology, molecular biology and genetic
engineering in the development of a nano-scale therapeutical vector became matter of …

[图书][B] Estudi de l'expressió i secreció de proteïnes recombinants (agarasa i lacasa) en una soca SipY-de Streptomyces lividans

M Vidal Gabarró - 2015 - ddd.uab.cat
La producció de proteïnes homòlogues i heteròlogues a escala industrial requereix
sistemes d'expressió variats i eficients. Els bacteris grampositius, com Streptomyces, poden …

A compact mathematical model of mandelate racemase production and chaperone overexpression in E. coli

B Kramer, R Tüngler, K Bettenbrock, C Conradi - IFAC-PapersOnLine, 2015 - Elsevier
E. coli is commonly used for recombinant protein production, eg in the pharmaceutical
industry for large-scale production of human insulin. A common problem arises from the …

[PDF][PDF] Biotecnología Farmacéutica, asignatura optativa de «obligado conocimiento» en el Grado de Farmacia (UCM)

AR Alcántara, MJ Hernáiz, JM Sánchez-Montero… - crinoidea.semicrobiologia.org
ESPECIAL se usan de manera indistinta, no deben confundirse1. En efecto, aunque puede
asumirse que «fármacos biológicos» se puede referir a cualquier compuesto farmacéutico …

Development of contamination resistance strategies for bioindustrial applications

EL Dul - 2015 - era.library.ualberta.ca
Contamination by lactic acid bacteria is a major source of inefficiency in the bioethanol
industry. Contaminated fermentations exhibit lowered ethanol yields and contamination …

[PDF][PDF] The unfolded protein response pre and post methanol induction of Komagataella (Pichia) pastoris producing secretory Insulin precursor

G Roth - 2015 - repo.uni-hannover.de
The methylotrophic yeast Pichia pastoris is an established eukaryotic expression system for
the production of heterologous proteins of biopharmaceutical or industrial interest, due to its …

[图书][B] Consequences of sequence variants for the expression of a dual targeting novel format antibody construct

C Gaffney - 2015 - search.proquest.com
Antibody engineering is an innovative field of research that has generated a wide range of
novel antibody-based formats that both exploit and improve natural antibody properties …

[图书][B] Exploring the diversity and productivity of clonal Chinese hamster ovary host cell lines derived from a non-clonal population

AR Jeavons - 2015 - search.proquest.com
Chinese hamster ovary (CHO) cell lines are the most frequently used mammalian host for
commercial production of recombinant protein-based biopharmaceuticals. Heterogeneity …