[HTML][HTML] Brain metabolism and Alzheimer's disease: the prospect of a metabolite-based therapy
The brain is one of the most energy-demanding organs in the body. It has evolved intricate
metabolic networks to fulfill this need and utilizes a variety of substrates to generate ATP, the …
metabolic networks to fulfill this need and utilizes a variety of substrates to generate ATP, the …
[HTML][HTML] Interaction of α-lipoic acid with the human Na+/multivitamin transporter (hSMVT)
B Zehnpfennig, P Wiriyasermkul, DA Carlson… - Journal of Biological …, 2015 - ASBMB
The human Na+/multivitamin transporter (hSMVT) has been suggested to transport α-lipoic
acid (LA), a potent antioxidant and anti-inflammatory agent used in therapeutic applications …
acid (LA), a potent antioxidant and anti-inflammatory agent used in therapeutic applications …
Lipoic acid and pentoxifylline mitigate nandrolone decanoate-induced neurobehavioral perturbations in rats via re-balance of brain neurotransmitters, up-regulation of …
MAE Ahmed, SA El-Awdan - Hormones and Behavior, 2015 - Elsevier
Behavioral perturbations associated with nandrolone decanoate abuse by athletes and
adolescents may be attributed to oxidative stress and inflammation. However, the underlying …
adolescents may be attributed to oxidative stress and inflammation. However, the underlying …
Photomediated Reactive Oxygen Species‐Generable Nanoparticles for Triggered Release and Endo/Lysosomal Escape of Drug upon Attenuated Single Light …
Nanoparticles with “smart” stimuli‐responsive materials and multiple therapeutic strategies
in a single delivery platform have emerged for highly efficient cancer therapy. Here …
in a single delivery platform have emerged for highly efficient cancer therapy. Here …
[HTML][HTML] Anti-oxidative and anti-inflammatory effects of lipoic acid in rat liver
A Goraca, H Huk-Kolega, A Kowalczyk… - Advances in Hygiene and …, 2015 - phmd.pl
Introduction: Lipopolysaccharide (LPS) is a key inflammatory component of Gram-negative
bacteria, which after entering the systemic circulation contributes to the development of …
bacteria, which after entering the systemic circulation contributes to the development of …
Aluminium phosphide-induced hepato-nephrotoxicity and oxidative damage in rats: the protective effect of α-lipoic acid
MI Yousef, NF Soliman… - The Open conference …, 2015 - benthamopen.com
The present experiment was carried out to investigate the effectivness of α-lipoic acid in
allevating the toxicity of aluminium phosphide on biochemical parameters, free radicals and …
allevating the toxicity of aluminium phosphide on biochemical parameters, free radicals and …
[HTML][HTML] Protective effects of SS31 on t‑BHP induced oxidative damage in 661W cells
The present study aimed to investigate the ability of SS31, a novel mitochondria‑targeted
peptide to protect against t‑BHP‑induced mitochondrial dysfunction and apoptosis in 661W …
peptide to protect against t‑BHP‑induced mitochondrial dysfunction and apoptosis in 661W …
[HTML][HTML] A prospective, proof-of-concept investigation of KPAX002 in chronic fatigue syndrome
JD Kaiser - International journal of clinical and experimental …, 2015 - ncbi.nlm.nih.gov
Stimulant drugs and various micronutrient interventions have previously been studied in
chronic fatigue syndrome (CFS) but they have never been studied in combination. This proof …
chronic fatigue syndrome (CFS) but they have never been studied in combination. This proof …
The effects of α-lipoic acid on immature rats with traumatic brain injury
S Ozbal, U Cankurt, K Tugyan, C Pekcetin… - Biotechnic & …, 2015 - Taylor & Francis
Traumatic brain injury (TBI) is a leading cause of morbidity and mortality during childhood.
TBI enhances formation of reactive oxygen species that cause neuron damage and …
TBI enhances formation of reactive oxygen species that cause neuron damage and …