Upcoming biological therapies in systemic lupus erythematosus

S Sciascia, E Talavera-Garcia, D Roccatello… - International …, 2015 - Elsevier
Systemic lupus erythematosus (SLE) is a chronic autoimmune condition with unpredictable
course, intermingled with flares and periods of remission. Although the prognosis of the …

Reviewing the recommendations for lupus in children

ZS Arıcı, ED Batu, S Ozen - Current Rheumatology Reports, 2015 - Springer
Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disorder with
severe morbidity and mortality and diverse systemic involvement. Disease onset occurs …

B cells biology in systemic lupus erythematosus—from bench to bedside

LD Zhao, YX Ye, X Zhang - Science China Life Sciences, 2015 - Springer
Systemic lupus erythematosus (SLE) is a debilitating autoimmune disease that can involve
multi-organs. B cells play a central role in the immunopathogenesis via antibody-dependent …

Achieving incompatible transplantation through desensitization: current perspectives and future directions

SC Jordan, J Choi, A Vo - Immunotherapy, 2015 - Taylor & Francis
The application of life-saving transplantation is severely limited by the shortage of organs,
and histoincompatibility. To increase transplant rates in sensitized patients, new protocols …

Biologic therapies in systemic lupus erythematosus

CB Bernal, LD Zamora… - International Journal of …, 2015 - Wiley Online Library
Significant progress has been made in the development of therapies for systemic lupus
erythematosus (SLE). These include agents which target interferons, cytokines, T …

Higher level of IL-6 in Jaccoud's arthropathy secondary to systemic lupus erythematosus: a perspective for its treatment?

AM Atta, RC Oliveira, IS Oliveira, MP Menezes… - Rheumatology …, 2015 - Springer
Jaccoud's arthropathy (JA) is a condition characterized clinically by 'reversible'joint
deformities along with an absence of articular erosions on a plain radiograph. The main …

Key issues in the management of patients with systemic lupus erythematosus: latest developments and clinical implications

N Jordan, D D'Cruz - Therapeutic Advances in …, 2015 - journals.sagepub.com
Systemic lupus erythematous (SLE) is a chronic multisystem disease with significant
associated morbidity and mortality. A deeper understanding of the pathogenesis of SLE has …

Safety of off-label biologicals in systemic lupus erythematosus

M Aringer, JS Smolen - Expert opinion on drug safety, 2015 - Taylor & Francis
Introduction: The approval of belimumab and other advances in the field have narrowed the
window for off-label use of biologicals in systemic lupus erythematosus (SLE). For …

[引用][C] Th 细胞相关因子与系统性红斑狼疮

吴萌, 杨金华, 介绍亮, 闫成兰, 陈俊伟 - 中华临床医师杂志: 电子版, 2015

Progress with the Use of Monoclonal Antibodies for the Treatment of Systemic Lupus Erythematosusd

N Jordan, PMK Lutalo, DP D'Cruz - Immunotherapy, 2015 - Taylor & Francis
In recent years, significant progress has been made in the use of monoclonal antibodies in
the treatment of systemic lupus erythematosus (SLE). Advances in our understanding of the …