Systemic lupus erythematosus (SLE) is a multi-systemic inflammatory disease with a broad
spectrum of clinical manifestations. This chronic autoimmune condition is characterized by a …

Background Systemic lupus erythematosus (SLE) is characterized by a breakdown of self-
tolerance against nuclear Ags leading to inflammation and multi-organ damage 1-2. The …

El LES es una enfermedad autoinmune de carácter sistémico. Dentro de la rareza global de
las enfermedades autoinmunes, el lupus es una de las más frecuentes. 3 En nuestro país …

Background: The immune system is important in epithelial ovarian cancer (EOC). Interleukin-
6 is associated with chemoresistance and an immune-suppressive tumor microenvironment …

요약 자가면역 질환에서 발생하는 대식세포 활성화 증후군 (MAS) 은 중증의 치명적인
합병증으로 전신홍반루푸스에서 드물게 발생한다. MAS 에서 특징적으로 보이는 발열, 혈구 …

The development of therapeutic monoclonal antibodies (mAb) has permitted targeted
therapy of rheumatic autoimmune/inflammatory diseases (RAID). A number of approaches …

Background The innate immune system contributes to the pathogenesis of SLE, in part
through the activity of Toll-like receptors (TLRs), a family of pattern-recognition receptors …

Background Cardiovascular disease (CVD) is a major cause of death in systemic lupus
erythematosus (SLE) patients. Obesity is an additional risk factor for cardiovascular disease …

Renal involvement occurs in 50–75% of children with childhood-onset systemic lupus
erythematosus (cSLE). Proliferative lupus nephritis (LN) represents the most common …

Abstract Renal involvement occurs in 50-75% of children with childhood-onset systemic
lupus erythematosus (cSLE). Proliferative lupus nephritis (LN) represents the most common …