Epigenetic aspects of systemic lupus erythematosus

M Relle, B Foehr, A Schwarting - Rheumatology and Therapy, 2015 - Springer
Autoimmune diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis,
multiple sclerosis, autoimmune hepatitis, and inflammatory bowel disease have complex …

Epigenetic signatures of internal migration in Italy

G Campanella, S Polidoro, C Di Gaetano… - International journal …, 2015 - academic.oup.com
Background: Observational studies have suggested that the risks of non-communicable
diseases in voluntary migrants become similar to those in the host population after one or …

Epigenetics in social insects

KM Glastad, LM Chau, MAD Goodisman - Advances in insect physiology, 2015 - Elsevier
Social insects enjoy great ecological success. The success of social insects stems from the
remarkable levels of phenotypic plasticity displayed by colony members. This …

Epigenetic inhibitors

M Verma, HN Banerjee - Cancer Epigenetics: Risk Assessment, Diagnosis …, 2015 - Springer
Traditional treatments for cancer include chemotherapy, radiation therapy, and surgery.
Recently, epigenetic inhibitors have been found to be very effective in cancer treatment …

ColoWeb: a resource for analysis of colocalization of genomic features

RG Kim, OK Smith, WC Wong, AM Ryan, MC Ryan… - BMC genomics, 2015 - Springer
Background Next-generation sequencing techniques such as ChIP-seq allow researchers to
investigate the genomic position of nuclear components and events. These experiments …

Epigenetic regulation of carotid body oxygen sensing: clinical implications

J Nanduri, NR Prabhakar - Arterial Chemoreceptors in Physiology and …, 2015 - Springer
Recurrent apnea with intermittent hypoxia (IH) is a major clinical problem in infants born
preterm. Recent epidemiological studies showed that adults who were born preterm exhibit …

Promoter hypermethylation and decreased expression of syncytin-1 in pancreatic adenocarcinomas

Q Lu, J Li, C Senkowski, Z Tang, J Wang, T Huang… - PLoS …, 2015 - journals.plos.org
Syncytin-1 is a member of human endogenous retroviral W gene family (HERVW1). Known
to be expressed in human placental trophoblast, syncytin-1 protein mediates the fusion of …

Epigenetics in ADPKD: understanding mechanisms and discovering treatment

X Li - Exon Publications, 2015 - exonpublications.com
Epigenetics is the study of all heritable changes in gene expression and chromatin
organization that are caused by mechanisms independent of the DNA sequence itself …

Measurement of postreplicative DNA metabolism and damage in the rodent brain

JP Patel, ML Sowers, JL Herring… - Chemical research in …, 2015 - ACS Publications
The DNA of all organisms is metabolically active due to persistent endogenous DNA
damage, repair, and enzyme-mediated base modification pathways important for epigenetic …

Gene expression and epigenetic profiles of mammary gland tissue: Insight into the differential predisposition of four rat strains to mammary gland cancer

L Luzhna, K Kutanzi, O Kovalchuk - Mutation Research/Genetic Toxicology …, 2015 - Elsevier
Rats are excellent experimental models for studying breast cancer, but rat strains differ in
susceptibility. Among the four strains used in this study, Fischer rats are less susceptible to …