Genetics and novel aspects of therapies in systemic lupus erythematosus

M Relle, J Weinmann-Menke, E Scorletti, L Cavagna… - Autoimmunity …, 2015 - Elsevier
Autoimmune diseases, such as rheumatoid arthritis, multiple sclerosis, autoimmune hepatitis
and inflammatory bowel disease, have complex pathogeneses and the factors which cause …

Genetic susceptibility to systemic lupus erythematosus in the genomic era

Y Deng, BP Tsao - Nature Reviews Rheumatology, 2010 - nature.com
Our understanding of the genetic basis of systemic lupus erythematosus (SLE) has been
rapidly advanced using large-scale, case–control, candidate gene studies as well as …

The genetic contribution to systemic lupus erythematosus.

LA Criswell - Bulletin of the NYU hospital for joint diseases, 2008 - search.ebscohost.com
We are currently witnessing an explosion of information about the genetic contribution to
complex human diseases such as systemic lupus erythematosus (SLE). These genetic …

Genetic polymorphisms and the clinical response to systemic lupus erythematosus treatment towards personalized medicine

MI Barliana, NN Afifah, R Amalia, L Hamijoyo… - Frontiers in …, 2022 - frontiersin.org
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by a
broad spectrum of clinical manifestations, an aberrant autoimmune response to self …

Exploring the etiopathogenesis of systemic lupus erythematosus: a genetic perspective

A Javinani, A Ashraf-Ganjouei, S Aslani, A Jamshidi… - Immunogenetics, 2019 - Springer
Systemic lupus erythematosus (SLE) is an autoimmune multi-organ disorder that presents
itself in a thousand ways. Its clinical course is extremely unpredictable, which makes …

Update on the genetics of systemic lupus erythematosus: genome-wide association studies and beyond

YC Kwon, S Chun, K Kim, A Mak - Cells, 2019 - mdpi.com
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of complex etiology
that primarily affects women of childbearing age. The development of SLE is attributed to the …

The genetics and molecular pathogenesis of systemic lupus erythematosus (SLE) in populations of different ancestry

GN Goulielmos, MI Zervou, VM Vazgiourakis… - Gene, 2018 - Elsevier
Systemic lupus erythematosus (SLE; OMIM 152700) is a highly heterogeneous disorder,
characterized by differences in autoantibody profile, serum cytokines, and a multi-system …

Systemic lupus erythematosus: old and new susceptibility genes versus clinical manifestations

JD Azevedo Silva, C Addobbati… - Current …, 2014 - ingentaconnect.com
Systemic Lupus Erythematosus (SLE) is one of the most relevant world-wide autoimmune
disorders. The formation of autoantibodies and the deposition of antibody-containing …

Preface and Overview: Genetics of SLE; A sine qua non for identification

T Shirai, S Hirose - International Reviews of Immunology, 2000 - Taylor & Francis
Clinical manifestations of systemic lupus erythematosus (SLE) are extremely diverse and
variable, mainly because SLE is a multi-factorial disease. Variable combinations of …

Genetics of human systemic lupus erythematosus: the emerging picture

SK Nath, J Kilpatrick, JB Harley - Current opinion in immunology, 2004 - Elsevier
Systemic lupus erythematosus (SLE) is a systemic autoimmune inflammatory disease with
partially understood etiology, which can affect virtually any organ. Despite suggestions to the …