Obesity and osteoarthritis, more than just wear and tear: pivotal roles for inflamed adipose tissue and dyslipidaemia in obesity-induced osteoarthritis
E Thijssen, A Van Caam, PM Van Der Kraan - Rheumatology, 2015 - academic.oup.com
OA is a degenerative joint disease characterized by articular cartilage degradation,
osteophyte formation, synovitis, and subchondral bone sclerosis. One of OAs main risk …
osteophyte formation, synovitis, and subchondral bone sclerosis. One of OAs main risk …
The role of fat and inflammation in the pathogenesis and management of osteoarthritis
H Urban, CB Little - Rheumatology, 2018 - academic.oup.com
OA is a complex disease involving mechanical, metabolic and inflammatory contributions to
its aetiology. A key risk factor, obesity, is becoming an increasing focus of research due to its …
its aetiology. A key risk factor, obesity, is becoming an increasing focus of research due to its …
Obesity and osteoarthritis: more than just wear and tear
RC Koonce, JT Bravman - … -Journal of the American Academy of …, 2013 - journals.lww.com
A link has been established between obesity and osteoarthritis (OA), but the precise
relationship has yet to be defined. OA has a multifactorial etiology, and obesity is …
relationship has yet to be defined. OA has a multifactorial etiology, and obesity is …
Is osteoarthritis a metabolic disease?
J Sellam, F Berenbaum - Joint bone spine, 2013 - Elsevier
Obesity, together with aging and injury, is among the main risk factors for osteoarthritis.
Obesity-related osteoarthritis can affect not only the weight-bearing joints, but also the …
Obesity-related osteoarthritis can affect not only the weight-bearing joints, but also the …
[HTML][HTML] Fundamentals of OA. An initiative of Osteoarthritis and Cartilage. Obesity and metabolic factors in OA
Objective Obesity was once considered a risk factor for knee osteoarthritis (OA) primarily for
biomechanical reasons. Here we provide an additional perspective by discussing how …
biomechanical reasons. Here we provide an additional perspective by discussing how …
Obesity and inflammation-targets for OA therapy
F Iannone, G Lapadula - Current drug targets, 2010 - ingentaconnect.com
Obesity is one of the main risk factors for osteoarthritis (OA). For many years the association
of obesity and OA has been simply attributed to the effects of overload on weight-bearing …
of obesity and OA has been simply attributed to the effects of overload on weight-bearing …
Obesity, Metabolic Syndrome, and Osteoarthritis—An Updated Review
SJP Sampath, V Venkatesan, S Ghosh… - Current Obesity …, 2023 - Springer
Abstract Purpose of Review Metabolic syndrome (MetS), also called the 'deadly
quartet'comprising obesity, diabetes, dyslipidemia, and hypertension, has been ascertained …
quartet'comprising obesity, diabetes, dyslipidemia, and hypertension, has been ascertained …
Pathobiology of obesity and osteoarthritis: integrating biomechanics and inflammation
RI Issa, TM Griffin - Pathobiology of Aging & Age-related Diseases, 2012 - Taylor & Francis
Obesity is a significant risk factor for developing osteoarthritis in weight-bearing and non-
weight-bearing joints. Although the pathogenesis of obesity-associated osteoarthritis is not …
weight-bearing joints. Although the pathogenesis of obesity-associated osteoarthritis is not …
Obesity punches above its weight in osteoarthritis
RM Aspden - Nature Reviews Rheumatology, 2011 - nature.com
Arthritis Research UK published a report in 2009 entitled “Osteoarthritis and obesity” in
which they highlight the severe consequences of obesity for musculoskeletal health …
which they highlight the severe consequences of obesity for musculoskeletal health …
[HTML][HTML] Osteoarthritis, obesity and type 2 diabetes: the weight of waist circumference
M Duclos - Annals of physical and rehabilitation medicine, 2016 - Elsevier
Background Obesity and type 2 diabetes (T2D) significantly increase the risk of developing
an arthritic condition. Methods We performed a review of literature on the pathophysiological …
an arthritic condition. Methods We performed a review of literature on the pathophysiological …