Systematic review, meta-analysis and economic modelling of molecular diagnostic tests for antibiotic resistance in tuberculosis.

F Drobniewski, M Cooke, J Jordan… - Health technology …, 2015 - researchonline.lshtm.ac.uk
BACKGROUND: Drug-resistant tuberculosis (TB), especially multidrug-resistant (MDR,
resistance to rifampicin and isoniazid) disease, is associated with a worse patient outcome …

Cost-effectiveness analysis of introduction of rapid, alternative methods to identify multidrug-resistant tuberculosis in middle-income countries

C Acuna-Villaorduna, A Vassall… - Clinical Infectious …, 2008 - academic.oup.com
Background. Resistance to commonly used antituberculosis drugs is emerging worldwide.
Conventional drug-susceptibility testing (DST) methods are slow and demanding …

[HTML][HTML] Comparison of laboratory costs of rapid molecular tests and conventional diagnostics for detection of tuberculosis and drug-resistant tuberculosis in South …

M Shah, V Chihota, G Coetzee, G Churchyard… - BMC infectious …, 2013 - Springer
Abstract Background The World Health Organization has endorsed the use of molecular
methods for the detection of TB and drug-resistant TB as a rapid alternative to culture-based …

Rapid molecular tests for tuberculosis and tuberculosis drug resistance: a qualitative evidence synthesis of recipient and provider views

N Engel, EA Ochodo, PW Karanja… - Cochrane Database …, 2022 - cochranelibrary.com
Background Programmes that introduce rapid molecular tests for tuberculosis and
tuberculosis drug resistance aim to bring tests closer to the community, and thereby cut …

Diagnostic accuracy of centralised assays for TB detection and detection of resistance to rifampicin and isoniazid: a systematic review and meta-analysis

M Kohli, E MacLean, M Pai… - European …, 2021 - Eur Respiratory Soc
Various diagnostic companies have developed high throughput molecular assays for
tuberculosis (TB) and resistance detection for rifampicin and isoniazid. We performed a …

[HTML][HTML] Systematic review of the performance of rapid rifampicin resistance testing for drug-resistant tuberculosis

M Arentz, B Sorensen, DJ Horne, JL Walson - PloS one, 2013 - journals.plos.org
Introduction Rapid tests for rifampicin resistance may be useful for identifying isolates at high
risk of drug resistance, including multidrug-resistant TB (MDR-TB). However, choice of …

GenoType MTBDR assays for the diagnosis of multidrug-resistant tuberculosis: a meta-analysis

DI Ling, AA Zwerling, M Pai - European Respiratory Journal, 2008 - Eur Respiratory Soc
The global extensively drug-resistant tuberculosis (TB) response plan calls for
implementation of rapid tests to screen patients at risk of drug-resistant TB. Currently, two …

GeneXpert MTB/RIF version G4 for identification of rifampin-resistant tuberculosis in a programmatic setting

M Osman, JA Simpson, J Caldwell… - Journal of clinical …, 2014 - Am Soc Microbiol
ABSTRACT A recent Cochrane review estimated GeneXpert MTB/RIF specificity for rifampin
resistance as 98%(95% confidence interval [CI], 97 to 99), based on results from earlier test …

[HTML][HTML] Direct susceptibility testing for multi drug resistant tuberculosis: a meta-analysis

F Bwanga, S Hoffner, M Haile, ML Joloba - BMC infectious diseases, 2009 - Springer
Background One of the challenges facing the tuberculosis (TB) control programmes in
resource-limited settings is lack of rapid techniques for detection of drug resistant TB …

The impact and cost-effectiveness of strategies to detect drug-resistant tuberculosis

O Oxlade, D Falzon, D Menzies - European Respiratory Journal, 2012 - Eur Respiratory Soc
Drug-resistant tuberculosis (TB) is a serious emerging problem in many low-resource
countries. TB control programmes are uncertain of which drug susceptibility tests (DSTs) to …