Design, synthesis, and biological evaluation of folate targeted photosensitizers for photodynamic therapy

LJ Donahue - 2015 - search.proquest.com
Photodynamic therapy (PDT) is used to treat cancer, and involves a highly conjugated
molecule, called a photosensitizer (PS), which is excited by wavelengths of light from visible …

Design, synthesis and biological evaluation of folate-targeted photodynamic therapy agents

GA Boateng - 2009 - search.proquest.com
Photodynamic therapy (PDT) is a cancer treatment approach that uses a tumor-localizing
drug called photosensitizer; this, when activated by light of an appropriate wavelength …

[HTML][HTML] Synthesis and Testing of Photosensitizer-Folate Conjugates and Potential Photosensitizers for Photodynamic Therapy

JA Trautmann - 2015 - ecommons.luc.edu
Photodynamic Therapy (PDT) is a technique that destroys oncogenic (cancerous) cells. It
has been used in several countries since the 1980's. Molecules that contain chromophores …

Design, synthesis, and biological evaluation of folic acid targeted tetraphenylporphyrin as novel photosensitizers for selective photodynamic therapy

R Schneider, F Schmitt, C Frochot, Y Fort… - Bioorganic & medicinal …, 2005 - Elsevier
Photodynamic therapy (PDT) is a cancer treatment involving systemic administration of a
tumor-localizing photosensitizer; this, when activated by the appropriate light wavelength …

Tumour-targeting photosensitisers for one-and two-photon activated photodynamic therapy

S Jenni, A Sour, F Bolze, B Ventura… - Organic & Biomolecular …, 2019 - pubs.rsc.org
Despite the advantages of photodynamic therapy (PDT) over chemotherapy or radiotherapy
such as low side effects, lack of treatment resistance and spatial selectivity inherent to light …

Folic acid conjugates with photosensitizers for cancer targeting in photodynamic therapy: Synthesis and photophysical properties

A Stallivieri, L Colombeau, G Jetpisbayeva… - Bioorganic & Medicinal …, 2017 - Elsevier
Recent researches in photodynamic therapy have focused on novel techniques to enhance
tumour targeting of anticancer drugs and photosensitizers. Coupling a photosensitizer with …

[图书][B] Development of folate directed, protein based photodynamic therapy agents

RJN Jones - 2016 - search.proquest.com
To attack cancer cells in a specific manner, we have developed a folate-targeted,
photodynamic therapy (PDT) agent. The folate (FA) and the chlorin e6 (Ce6) photosensitizer …

Cancer-selective photodynamic therapy via photosensitizer conjugates with folate

이주영, 김경섭, 나건 - 한국공업화학회연구논문초록집, 2019 - kiss.kstudy.com
Hydrophilic photosensitizers (HP) are appropriate wavelength light susceptible molecules
that are essential for photodynamic therapy (PDT). The photosensitizers absorb photon …

The interest of folic acid in targeted photodynamic therapy

A Stallivieri, F Baros, G Jetpisbayeva… - Current medicinal …, 2015 - ingentaconnect.com
Photodynamic therapy is an alternative to chemotherapy and radiotherapy for cancer
treatment. PDT is clinically applied to treat age-related macular degeneration and several …

Synthesis of a Folate-Mediated Photodynamic Therapy Agent and Application in Zebrafish Embryos

A Kothawala, A Monterastelli, P Pham - 2021 - ecommons.luc.edu
This project investigates the use of folate for targeted delivery of photosensitizers to tumors
in photodynamic therapy. A photosensitizer, chlorin e6, produces toxic singlet oxygen …