[HTML][HTML] Naringin ameliorates cognitive deficits via oxidative stress, proinflammatory factors and the PPARγ signaling pathway in a type 2 diabetic rat model

Z Qi, Y Xu, Z Liang, S Li, J Wang… - Molecular …, 2015 - spandidos-publications.com
Naringenin is a flavonoid polyphenolic compound, which facilitates the removal of free
radicals, oxidative stress and inflammation. The present study aimed to obtain a better …

[HTML][HTML] Naringin ameliorates cognitive deficits in streptozotocin-induced diabetic rats

X Liu, M Liu, Y Mo, H Peng, J Gong, Z Li… - Iranian Journal of …, 2016 - ncbi.nlm.nih.gov
Objective (s): Previous research demonstrated that diabetes is one of the leading causes of
learning and memory deficits. Naringin, a bioflavonoid isolated from grapefruits and …

Participation of antioxidant and cholinergic system in protective effect of naringenin against type-2 diabetes-induced memory dysfunction in rats

A Rahigude, P Bhutada, S Kaulaskar, M Aswar, K Otari - Neuroscience, 2012 - Elsevier
Naringenin is a flavone flavonoid possessing antidiabetic, antioxidant and memory
improving effects. Therefore, we studied the influence of naringenin against type-2 diabetes …

[HTML][HTML] Strawberry leaf extract treatment alleviates cognitive impairment by activating Nrf2/HO-1 signaling in rats with streptozotocin-induced diabetes

L Zhang, Q Ma, Y Zhou - Frontiers in Aging Neuroscience, 2020 - frontiersin.org
Diabetes-associated cognitive impairment (DACI) is a common complication of diabetes
mellitus (DM) that affects the central nervous system. Cognitive impairment, such as learning …

[HTML][HTML] Curcumin and its analog alleviate diabetes-induced damages by regulating inflammation and oxidative stress in brain of diabetic rats

C Miao, H Chen, Y Li, Y Guo, F Xu, Q Chen… - Diabetology & Metabolic …, 2021 - Springer
Background Diabetic encephalopathy is a severe diabetes complication with cognitive
dysfunction and neuropsychiatric disability. The mechanisms underlying diabetic …

Naringin Prevents Cognitive Dysfunction in Aging Rats by Inhibiting Toll‐Like Receptor 4 (TLR4)/NF‐κB Pathway and Endoplasmic Reticulum Stress

X Dai, Y Jia, R Cao, M Zhou - Evidence‐Based Complementary …, 2023 - Wiley Online Library
Objective. Naringin is a flavonoid derived from Chinese herbs. According to earlier studies,
naringin may have the potential to alleviate aging‐induced cognitive dysfunction. Therefore …

[HTML][HTML] Naringin attenuates the diabetic neuropathy in STZ-induced type 2 diabetic Wistar rats

MF Ahmad, N Naseem, I Rahman, N Imam, H Younus… - Life, 2022 - mdpi.com
The application of traditional medicines for the treatment of diseases, including diabetic
neuropathy (DN), has received great attention. The aim of this study was to investigate the …

Dihydromyricetin improves type 2 diabetes-induced cognitive impairment via suppressing oxidative stress and enhancing brain-derived neurotrophic factor-mediated …

H Ling, Z Zhu, J Yang, J He, S Yang… - Acta Biochimica et …, 2018 - academic.oup.com
Type 2 diabetes mellitus (T2DM) leads to cognitive impairment (CI), but there have been no
effective pharmacotherapies or drugs for cognitive dysfunction in T2DM. Dihydromyricetin …

Resveratrol prevents cognitive impairment in type 2 diabetic mice by upregulating Nrf2 expression and transcriptional level

X Wang, H Fang, G Xu, Y Yang, R Xu… - Diabetes, Metabolic …, 2020 - Taylor & Francis
Purpose This study aimed to determine whether the natural antioxidant resveratrol (RSV)
prevents type 2 diabetes mellitus (T2DM)-induced cognitive impairment and to explore …

Quercetin protects against diabetic encephalopathy via SIRT1/NLRP3 pathway in db/db mice

T Hu, XY Lu, JJ Shi, XQ Liu, QB Chen… - Journal of cellular …, 2020 - Wiley Online Library
Epidemiological studies have found that diabetes and cognitive dysfunction are closely
related. Quercetin has been certified with the effect on improving diabetes mellitus (DM) and …