[HTML][HTML] Thematic Review Series: Intestinal Lipid Metabolism: New Developments and Current Insights: Intestinal triacylglycerol synthesis in fat absorption and …
CLE Yen, DW Nelson, MI Yen - Journal of Lipid Research, 2015 - ncbi.nlm.nih.gov
The intestine plays a prominent role in the biosynthesis of triacylglycerol (triglyceride; TAG).
Digested dietary TAG is repackaged in the intestine to form the hydrophobic core of …
Digested dietary TAG is repackaged in the intestine to form the hydrophobic core of …
[HTML][HTML] Intestinal triacylglycerol synthesis in fat absorption and systemic energy metabolism
CLE Yen, DW Nelson, MI Yen - Journal of lipid research, 2015 - ASBMB
The intestine plays a prominent role in the biosynthesis of triacylglycerol (triglyceride; TAG).
Digested dietary TAG is repackaged in the intestine to form the hydrophobic core of …
Digested dietary TAG is repackaged in the intestine to form the hydrophobic core of …
[HTML][HTML] DGAT1 is not essential for intestinal triacylglycerol absorption or chylomicron synthesis
Dietary triacylglycerols are a major source of energy for animals. The absorption of dietary
triacylglycerols involves their hydrolysis to free fatty acids and monoacylglycerols in the …
triacylglycerols involves their hydrolysis to free fatty acids and monoacylglycerols in the …
Dgat1 and Dgat2 regulate enterocyte triacylglycerol distribution and alter proteins associated with cytoplasmic lipid droplets in response to dietary fat
YH Hung, AL Carreiro, KK Buhman - … Acta (BBA)-Molecular and Cell Biology …, 2017 - Elsevier
Enterocytes, the absorptive cells of the small intestine, mediate efficient absorption of dietary
fat (triacylglycerol, TAG). The digestive products of dietary fat are taken up by enterocytes, re …
fat (triacylglycerol, TAG). The digestive products of dietary fat are taken up by enterocytes, re …
[HTML][HTML] Acylation of Acylglycerols by Acyl Coenzyme A: Diacylglycerol Acyltransferase 1 (DGAT1): Functional importance of DGAT1 in the intestinal fat absorption
D Cheng, J Iqbal, J Devenny, CH Chu, L Chen… - Journal of biological …, 2008 - ASBMB
Acyl coenzyme A: diacylglycerol acyltransferase 1 (DGAT1) is one of the four intestinal
membrane bound acyltransferases implicated in dietary fat absorption. Recently, it was …
membrane bound acyltransferases implicated in dietary fat absorption. Recently, it was …
Intestinal acyl-CoA: diacylglycerol acyltransferase 2 overexpression enhances postprandial triglyceridemic response and exacerbates high fat diet-induced hepatic …
Intestinal acyl-CoA: diacylglycerol acyltransferase 2 (DGAT2) is important in the cellular and
physiological responses to dietary fat. To determine the effect of increased intestinal DGAT2 …
physiological responses to dietary fat. To determine the effect of increased intestinal DGAT2 …
Diacylglycerol acyltransferase 1/2 inhibition induces dysregulation of fatty acid metabolism and leads to intestinal barrier failure and diarrhea in mice
K Takemoto, Y Fukasaka, R Yoshimoto… - Physiological …, 2020 - Wiley Online Library
The intestinal metabolism and transport of triacylglycerol (TAG) play a critical role in dietary
TAG absorption, and defects in the process are associated with congenital diarrhea. The …
TAG absorption, and defects in the process are associated with congenital diarrhea. The …
[HTML][HTML] Diacylglycerol acyltransferase-1 inhibition enhances intestinal fatty acid oxidation and reduces energy intake in rats [S]
Acyl CoA: diacylglycerol acyltransferase-1 (DGAT-1) catalyzes the final step in triacylglycerol
(TAG) synthesis and is highly expressed in the small intestine. Because DGAT-1 knockout …
(TAG) synthesis and is highly expressed in the small intestine. Because DGAT-1 knockout …
Mechanisms of intestinal triacylglycerol synthesis
SJ Stone - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2022 - Elsevier
Triacylglycerols are a major source of stored energy that are obtained either from the diet or
can be synthesized to some extent by most tissues. Alterations in pathways of triacylglycerol …
can be synthesized to some extent by most tissues. Alterations in pathways of triacylglycerol …
[HTML][HTML] Intestine-specific expression of acyl CoA: diacylglycerol acyltransferase 1 reverses resistance to diet-induced hepatic steatosis and obesity in Dgat1−/− mice
Mice deficient in acyl-CoA: diacylglycerol acyltransferase 1 (DGAT1), a key enzyme in
triacylglycerol (TG) biosynthesis, are resistant to high-fat (HF) diet-induced hepatic steatosis …
triacylglycerol (TG) biosynthesis, are resistant to high-fat (HF) diet-induced hepatic steatosis …