Fracture healing: mechanisms and interventions
TA Einhorn, LC Gerstenfeld - Nature Reviews Rheumatology, 2015 - nature.com
Fractures are the most common large-organ, traumatic injuries to humans. The repair of
bone fractures is a postnatal regenerative process that recapitulates many of the ontological …
bone fractures is a postnatal regenerative process that recapitulates many of the ontological …
Trauma-induced inflammation and fracture healing
HC Pape, R Marcucio, C Humphrey… - … of orthopaedic trauma, 2010 - journals.lww.com
Fracture healing is an extremely complex interaction of cells, biologic pathways, and
molecules. Certainly, the inflammatory response is one of the initiating factors for bone …
molecules. Certainly, the inflammatory response is one of the initiating factors for bone …
Bone injury and fracture healing biology
Bones are organs of the skeletal system, providing shape, mechanical support, and
protection to the body and facilitating the movement. In addition, bones contribute to the …
protection to the body and facilitating the movement. In addition, bones contribute to the …
Overview of the fracture healing cascade
AM Phillips - Injury, 2005 - Elsevier
Fracture healing is a dynamic process being governed by a variety of cellular elements and
stimulating agents. Our knowledge in understanding the molecular and cellular processes …
stimulating agents. Our knowledge in understanding the molecular and cellular processes …
The biology of fracture healing
R Marsell, TA Einhorn - Injury, 2011 - Elsevier
The biology of fracture healing is a complex biological process that follows specific
regenerative patterns and involves changes in the expression of several thousand genes …
regenerative patterns and involves changes in the expression of several thousand genes …
Inflammation, fracture and bone repair
The reconstitution of lost bone is a subject that is germane to many orthopedic conditions
including fractures and non-unions, infection, inflammatory arthritis, osteoporosis …
including fractures and non-unions, infection, inflammatory arthritis, osteoporosis …
The control of fracture healing and its therapeutic targeting: improving upon nature
DE Komatsu, SJ Warden - Journal of cellular biochemistry, 2010 - Wiley Online Library
Fracture repair is a complex process involving timed cellular recruitment, gene expression,
and synthesis of compounds that regenerate native tissue to restore the mechanical …
and synthesis of compounds that regenerate native tissue to restore the mechanical …
Current concepts of molecular aspects of bone healing
R Dimitriou, E Tsiridis, PV Giannoudis - Injury, 2005 - Elsevier
Fracture healing is a complex physiological process. It involves the coordinated participation
of haematopoietic and immune cells within the bone marrow in conjunction with vascular …
of haematopoietic and immune cells within the bone marrow in conjunction with vascular …
Cellular biology of fracture healing
CS Bahney, RL Zondervan, P Allison… - Journal of …, 2019 - Wiley Online Library
The biology of bone healing is a rapidly developing science. Advances in transgenic and
gene‐targeted mice have enabled tissue and cell‐specific investigations of skeletal …
gene‐targeted mice have enabled tissue and cell‐specific investigations of skeletal …
Recent developments in the biology of fracture repair
FNK Kwong, MB Harris - … -Journal of the American Academy of …, 2008 - journals.lww.com
Fracture repair is dependent on local and systemic molecular and cellular processes. During
fracture repair, mesenchymal stem cells are systemically recruited to the fracture site, and …
fracture repair, mesenchymal stem cells are systemically recruited to the fracture site, and …