Ebola Virus and Severe Acute Respiratory Syndrome Coronavirus Display Late Cell Entry Kinetics: Evidence that Transport to NPC1+ Endolysosomes Is a Rate …
RM Mingo, JA Simmons, CJ Shoemaker… - Journal of …, 2015 - Am Soc Microbiol
Ebola virus (EBOV) causes hemorrhagic fevers with high mortality rates. During cellular
entry, the virus is internalized by macropinocytosis and trafficked through endosomes until …
entry, the virus is internalized by macropinocytosis and trafficked through endosomes until …
Ebola virus enters host cells by macropinocytosis and clathrin-mediated endocytosis
P Aleksandrowicz, A Marzi, N Biedenkopf… - The Journal of …, 2011 - academic.oup.com
Virus entry into host cells is the first step of infection and a crucial determinant of
pathogenicity. Here we show that Ebola virus-like particles (EBOV-VLPs) composed of the …
pathogenicity. Here we show that Ebola virus-like particles (EBOV-VLPs) composed of the …
Ebolavirus Is Internalized into Host Cells via Macropinocytosis in a Viral Glycoprotein-Dependent Manner
A Nanbo, M Imai, S Watanabe, T Noda… - PLoS …, 2010 - journals.plos.org
Ebolavirus (EBOV) is an enveloped, single-stranded, negative-sense RNA virus that causes
severe hemorrhagic fever with mortality rates of up to 90% in humans and nonhuman …
severe hemorrhagic fever with mortality rates of up to 90% in humans and nonhuman …
Analysis of Ebola virus entry into macrophages
F Dahlmann, N Biedenkopf, A Babler… - The Journal of …, 2015 - academic.oup.com
Ebolaviruses constitute a public health threat, particularly in Central and Western Africa.
Host cell factors required for spread of ebolaviruses may serve as targets for antiviral …
Host cell factors required for spread of ebolaviruses may serve as targets for antiviral …
Cellular entry of ebola virus involves uptake by a macropinocytosis-like mechanism and subsequent trafficking through early and late endosomes
MF Saeed, AA Kolokoltsov, T Albrecht… - PLoS …, 2010 - journals.plos.org
Zaire ebolavirus (ZEBOV), a highly pathogenic zoonotic virus, poses serious public health,
ecological and potential bioterrorism threats. Currently no specific therapy or vaccine is …
ecological and potential bioterrorism threats. Currently no specific therapy or vaccine is …
Transport of Ebolavirus nucleocapsids is dependent on actin polymerization: live-cell imaging analysis of Ebolavirus-infected cells
G Schudt, O Dolnik, L Kolesnikova… - The Journal of …, 2015 - academic.oup.com
Background. Transport of ebolavirus (EBOV) nucleocapsids from perinuclear viral
inclusions, where they are formed, to the site of budding at the plasma membrane …
inclusions, where they are formed, to the site of budding at the plasma membrane …
Ebola virus exploits a monocyte differentiation program to promote its entry
O Martinez, JC Johnson, A Honko, B Yen… - Journal of …, 2013 - Am Soc Microbiol
Antigen-presenting cells (APCs) are critical targets of Ebola virus (EBOV) infection in vivo.
However, the susceptibility of monocytes to infection is controversial. Studies indicate …
However, the susceptibility of monocytes to infection is controversial. Studies indicate …
Induction of cell-cell fusion by Ebola virus glycoprotein: low pH is not a trigger
RM Markosyan, C Miao, YM Zheng, GB Melikyan… - PLoS …, 2016 - journals.plos.org
Ebola virus (EBOV) is a highly pathogenic filovirus that causes hemorrhagic fever in humans
and animals. Currently, how EBOV fuses its envelope membrane within an endosomal …
and animals. Currently, how EBOV fuses its envelope membrane within an endosomal …
Ebolavirus Glycoprotein Directs Fusion through NPC1+ Endolysosomes
JA Simmons, RS D'Souza, M Ruas, A Galione… - Journal of …, 2016 - Am Soc Microbiol
Ebolavirus, a deadly hemorrhagic fever virus, was thought to enter cells through
endolysosomes harboring its glycoprotein receptor, Niemann-Pick C1. However, an …
endolysosomes harboring its glycoprotein receptor, Niemann-Pick C1. However, an …
Detection of cell-cell fusion mediated by Ebola virus glycoproteins
S Bär, A Takada, Y Kawaoka, M Alizon - Journal of virology, 2006 - Am Soc Microbiol
Ebola viruses (EboV) are enveloped RNA viruses infecting cells by a pH-dependent process
mediated by viral glycoproteins (GP) involving endocytosis of virions and their routing into …
mediated by viral glycoproteins (GP) involving endocytosis of virions and their routing into …