Ebola virus (EBOV) causes hemorrhagic fevers with high mortality rates. During cellular
entry, the virus is internalized by macropinocytosis and trafficked through endosomes until …

Virus entry into host cells is the first step of infection and a crucial determinant of
pathogenicity. Here we show that Ebola virus-like particles (EBOV-VLPs) composed of the …

Ebolavirus (EBOV) is an enveloped, single-stranded, negative-sense RNA virus that causes
severe hemorrhagic fever with mortality rates of up to 90% in humans and nonhuman …

Ebolaviruses constitute a public health threat, particularly in Central and Western Africa.
Host cell factors required for spread of ebolaviruses may serve as targets for antiviral …

Zaire ebolavirus (ZEBOV), a highly pathogenic zoonotic virus, poses serious public health,
ecological and potential bioterrorism threats. Currently no specific therapy or vaccine is …

Background. Transport of ebolavirus (EBOV) nucleocapsids from perinuclear viral
inclusions, where they are formed, to the site of budding at the plasma membrane …

Antigen-presenting cells (APCs) are critical targets of Ebola virus (EBOV) infection in vivo.
However, the susceptibility of monocytes to infection is controversial. Studies indicate …

Ebola virus (EBOV) is a highly pathogenic filovirus that causes hemorrhagic fever in humans
and animals. Currently, how EBOV fuses its envelope membrane within an endosomal …

Ebolavirus, a deadly hemorrhagic fever virus, was thought to enter cells through
endolysosomes harboring its glycoprotein receptor, Niemann-Pick C1. However, an …

Ebola viruses (EboV) are enveloped RNA viruses infecting cells by a pH-dependent process
mediated by viral glycoproteins (GP) involving endocytosis of virions and their routing into …