Fucosyltransferase 2: a genetic risk factor for primary sclerosing cholangitis and Crohn's disease—a comprehensive review
L Maroni, SFJ van de Graaf, SD Hohenester… - Clinical reviews in …, 2015 - Springer
Abstract Fucosyltransferase 2 (FUT2) mediates the inclusion of fucose in sugar moieties of
glycoproteins and glycolipids. ABO blood group antigens and host-microbe interactions are …
glycoproteins and glycolipids. ABO blood group antigens and host-microbe interactions are …
[HTML][HTML] Fucosyltransferase 2: a genetic risk factor for intestinal diseases
M Hu, X Zhang, J Li, L Chen, X He, T Sui - Frontiers in Microbiology, 2022 - frontiersin.org
The fucosyltransferase 2 gene (FUT2) mediates the synthesis of histoblood group antigens
(HBGA) that occur in vivo from multiple organs, particularly on the surface of intestinal …
(HBGA) that occur in vivo from multiple organs, particularly on the surface of intestinal …
[PDF][PDF] Knockout of the primary sclerosing cholangitis‐risk gene Fut2 causes liver disease in mice
L Maroni, SD Hohenester, SFJ van de Graaf… - …, 2017 - Wiley Online Library
The etiopathogenesis of primary sclerosing cholangitis is unknown. Genetic variants of
fucosyltransferase 2 (FUT2) have been identified in genome‐wide association studies as …
fucosyltransferase 2 (FUT2) have been identified in genome‐wide association studies as …
Association of fucosyltransferase 2 gene polymorphisms with inflammatory bowel disease in patients from Southeast China
Aims. Fucosyltransferase 2 (FUT2) gene potentially affects the constituent of intestinal
microbiota, which play a crucial role in the pathogenesis of inflammatory bowel disease …
microbiota, which play a crucial role in the pathogenesis of inflammatory bowel disease …
Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease
Genetic variation in both innate and adaptive immune systems is associated with Crohn's
disease (CD) susceptibility, but much of the heritability to CD remains unknown. We …
disease (CD) susceptibility, but much of the heritability to CD remains unknown. We …
Association study of FUT2 (rs601338) with celiac disease and inflammatory bowel disease in the Finnish population
AS Parmar, N Alakulppi, P Paavola‐Sakki… - Tissue …, 2012 - Wiley Online Library
Homozygosity for a nonsense mutation in the fucosyltransferase 2 (FUT2) gene
(rs601338G> A) leads to the absence of ABH blood groups (FUT2 non‐secretor status) in …
(rs601338G> A) leads to the absence of ABH blood groups (FUT2 non‐secretor status) in …
[HTML][HTML] Association of fucosyltransferase 2 gene variants with ulcerative colitis in Han and Uyghur patients in China
A Aheman, HS Luo, F Gao - World Journal of Gastroenterology …, 2012 - ncbi.nlm.nih.gov
AIM: To investigate the contribution of fucosyltransferase 2 (FUT2) variants to the genetic
susceptibility and clinical heterogeneity of ulcerative colitis (UC) between Han and Uyghur …
susceptibility and clinical heterogeneity of ulcerative colitis (UC) between Han and Uyghur …
Fut2 genotype is a risk factor for dominant stenosis and biliary candida infections in primary sclerosing cholangitis
C Rupp, K Friedrich, T Folseraas… - Alimentary …, 2014 - Wiley Online Library
Background A recent genome‐wide association study identified the FUT 2 secretor status
and genotype defined by the single‐nucleotide polymorphism rs601338 as potential genetic …
and genotype defined by the single‐nucleotide polymorphism rs601338 as potential genetic …
Association of FUT2 and ABO with Crohn's disease in Koreans
Abstract Background and Aim Fucosyltransferase 2 (FUT2) at 19q13 is a well‐established
susceptibility locus for Crohn's disease (CD) in Caucasians. FUT2 encodes α‐1, 2 …
susceptibility locus for Crohn's disease (CD) in Caucasians. FUT2 encodes α‐1, 2 …
Core fucosylation on T cells, required for activation of T-cell receptor signaling and induction of colitis in mice, is increased in patients with inflammatory bowel disease
H Fujii, S Shinzaki, H Iijima, K Wakamatsu, C Iwamoto… - Gastroenterology, 2016 - Elsevier
Background & Aims Attachment of a fucose molecule to the innermost N-glycan in a
glycoprotein (core fucosylation) regulates the activity of many growth factor receptors and …
glycoprotein (core fucosylation) regulates the activity of many growth factor receptors and …
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