Engineering of large vascularized adipose tissue constructs is still a challenge for the
treatment of extensive high-graded burns or the replacement of tissue after tumor removal …

The development of in vitro adipose tissue constructs is highly desired to cope with the
increased demand for substitutes to replace damaged soft tissue after high graded burns …

Vascularization is still one of the most important limitations for the survival of engineered
tissues after implantation. In this study, we aim to improve the in vivo vascularization of …

In vitro adipose tissue models can be used to provide insight into fundamental aspects of
adipose physiology. These systems may serve as replacements for animal models, which …

The composition of vascularized adipose tissue is still an ongoing challenge as no culture
medium is available to supply adipocytes and endothelial cells appropriately. Endothelial …

Adipose tissue is an abundant, accessible, and uniquely dispensable source of cells for
vascular tissue engineering. Despite its intrinsic endothelial cells, considerable effort is …

Background: Autologous fat grafting has been a widely used technique; however, the role of
adipose-derived stem cells (ASCs), extracellular matrix (ECM), and microenvironment in fat …

Tissue-engineered constructs need to become quickly vascularized in order to ensure graft
take. One way of achieving this is to incorporate endothelial cells (EC) into the construct. The …

One of the current challenges in the field of adipose tissue engineering is to promote
sufficient vascularization to prevent cell death and to support adipose tissue formation. Thus …

Central to the development of adipose tissue (AT) engineered models is the supporting
vasculature. It is a key part of AT function and long-term maintenance, but the crosstalk …