In this study, six new compounds containing morpholine and 5 (4 H)-oxazolone rings were
synthesized. Structures of the new compounds using IR, 1 H NMR, mass spectroscopy and …

Abstract Tyrosinase (EC 1.14. 18.1) is a key copper-containing metalloenzyme widely
distributed in nature and plays determinant role in melanin biosynthesis. The enzyme …

Two series of novel kojic acid analogues (4a–j) and (5a–d) were designed and synthesized,
and their mushroom tyrosinase inhibitory activities was evaluated. The result indicated that …

In the present paper, we report the synthesis and pharmacological evaluation of a new
series of azo compounds with different groups (1‐naphthol, 2‐naphthol, and N, N …

In this study, twenty 3, 5-diaryl-4, 5-dihydro-1H-pyrazole derivatives with hydroxyl (s)(1a–1p,
2a–2d) were synthesized and their inhibitory activity on mushroom tyrosinase was …

Background and aim Tyrosinase (EC 1.14. 18.1) is responsible for enzymatic browning in
fruits and vegetables. Its inhibitors may be applied to efficiently treat hyperpigmentation and …

Six new azo dyes containing of 5 (4H)-oxazolone ring were prepared by diazotization of 4-
aminohippuric acid and coupling with N, N-dimethylaniline, 1-naphthol and 2-naphthol and …

In continuing our search for novel tyrosinase inhibitors, a series of 5-(substituted
benzylidene) thiazolidine-2, 4-diones were rationally designed and synthesized, and their …

A series of alkylidenethiosemicarbazide compounds were synthesized and their inhibitory
effects on the diphenolase activity of mushroom tyrosinase were evaluated. The results …

A series of coumarinyl-pyrazolinyl substituted thiazoles derivatives were synthesized and
their inhibitory effects on the DPPH and mushroom tyrosinase were evaluated. The results …