[HTML][HTML] Withania somnifera extract reduces the invasiveness of MDA-MB-231 breast cancer and inhibits cytokines associated with metastasis

KF Khazal, DL Hill - Journal of cancer metastasis and treatment, 2015 - ncbi.nlm.nih.gov
Aim The aim was to examine the anti-proliferative effect of a Withania somnifera (WS) root
extract in cell cultures and nude mouse xenografts of breast cancer cell line MDA-MB-231 …

[PDF][PDF] In vitro antiproliferative activity of partially purified Withania somnifera fruit extract on different cancer cell lines

N Abutaha - J BUON, 2015 - researchgate.net
Purpose: Cancer is a major health problem worldwide. There is a continuous need to search
for safer and more effective alternatives to overcome the side effects and resistance of the …

[HTML][HTML] Withania somnifera Root Extract Inhibits Mammary Cancer Metastasis and Epithelial to Mesenchymal Transition

Z Yang, A Garcia, S Xu, DR Powell, PM Vertino… - PLoS …, 2013 - journals.plos.org
Though clinicians can predict which patients are at risk for developing metastases,
traditional therapies often prove ineffective and metastatic disease is the primary cause of …

Evaluation and comparison of the in vitro cytotoxic activity of Withania somnifera Methanolic and ethanolic extracts against MDA-MB-231 and Vero cell lines

AN Srivastava, R Ahmad, MA Khan - Scientia pharmaceutica, 2016 - mdpi.com
Withania somnifera Dunal (WS), commonly known as Ashwagandha in India, belongs to the
family Solanaceae. It is extensively used in most of the Indian herbal pharmaceuticals and …

[PDF][PDF] Immunomodulatory activity in tumor-bearing mice treated with Withania somnifera extract

A Melo, AL de Melo, MC Marcucci, C Carvalho… - JAPLR, 2021 - researchgate.net
We investigated some actions of Withania somnifera on the growth and differentiation of
hematopoietic precursors [granulocyte/macrophage colony cell formation (CFU-GM)] of …

Antioxidant, anticancer and antibacterial activity of Withania somnifera aqueous root extract

DA Barnes, R Barlow, PS Nigam… - 2015 - chesterrep.openrepository.com
Aims: To evaluate total antioxidant capacity, anticancer activity and antibacterial effects
Withania somnifera aqueous-root extracts. Study Design: In vitro study. Place of Study …

[HTML][HTML] Withania somnifera: Progress towards a Pharmaceutical Agent for Immunomodulation and Cancer Therapeutics

VK Kashyap, G Peasah-Darkwah, A Dhasmana… - Pharmaceutics, 2022 - mdpi.com
Chemotherapy is one of the prime treatment options for cancer. However, the key issues
with traditional chemotherapy are recurrence of cancer, development of resistance to …

Effect of Withania somnifera on B16F‐10 melanoma induced metastasis in mice

PV Leyon, G Kuttan - Phytotherapy Research: An International …, 2004 - Wiley Online Library
Withania somnifera, a plant with known immunopotentiating activity and its bioactive fraction-
Withanolide D were studied for their anti-metastatic activity using B16F-10 melanoma cells …

Effect of Withania somnifera root extract on spontaneous estrogen receptor-negative mammary cancer in MMTV/Neu mice

KF Khazal, DL Hill, CJ Grubbs - Anticancer research, 2014 - ar.iiarjournals.org
The cancer-preventive activity of an extract of Withania somnifera (WS) roots was examined
in female transgenic (MMTV/Neu) mice that received a diet containing the extract (750 mg/kg …

[HTML][HTML] Withania somnifera Root Extract Has Potent Cytotoxic Effect against Human Malignant Melanoma Cells

B Halder, S Singh, SS Thakur - PLoS One, 2015 - journals.plos.org
In Ayurveda, Withania somnifera is commonly known as Ashwagandha, its roots are
specifically used in medicinal and clinical applications. It possesses numerous therapeutic …