Obesity is a major health burden with an increased risk of cardiovascular morbidity and
mortality. Endothelial dysfunction is pivotal to the development of cardiovascular disease …

Obesity, the most common nutritional disorder in industrial countries, is associated with
increased cardiovascular mortality and morbidity. Nevertheless, the molecular basis linking …

The metabolic syndrome comprises a cluster of cardiometabolic risk factors, with insulin
resistance and adiposity as its central features. Identifying individuals with metabolic …

Adipose tissue is a highly dynamic endocrine organ, secreting a number of bioactive
substances (adipokines) regulating insulin sensitivity, energy metabolism and vascular …

Adipose tissue has recently emerged as an active endocrine organ that secretes a variety of
metabolically important substances, collectively called adipocytokines or adipokines. In this …

Obesity, adiponectin and vascular inflammatory disease : Current Opinion in Lipidology
Obesity, adiponectin and vascular inflammatory disease : Current Opinion in Lipidology Log in …

The concept that fat cells could influence the circulation and indeed cardiac function has
been in existence for≥ 20 years and has gained a wide interest and no less excitement as …

Background and Purpose Adiponectin, the most abundant peptide secreted by adipocytes,
is involved in the regulation of energy metabolism and vascular physiology. Here, we have …

Studies of adipose tissue biology have demonstrated that adipose tissue should be
considered as both passive, energy-storing tissue and an endocrine organ because of the …

Rosiglitazone is a PPARγ agonist commonly used to treat diabetes. In addition to improving
insulin sensitivity, rosiglitazone restores normal vascular function by a mechanism that …