Impact of precise modulation of reactive oxygen species levels on spermatozoa proteins in infertile men

A Ayaz, A Agarwal, R Sharma, M Arafa, H Elbardisi… - Clinical Proteomics, 2015 - Springer
Background Elevated levels of reactive oxygen species (ROS) are detected in 25% to 80%
of infertile men. They are involved in the pathology of male infertility. Understanding the …

Proteomic analysis of human spermatozoa proteins with oxidative stress

R Sharma, A Agarwal, G Mohanty, AJ Hamada… - Reproductive Biology …, 2013 - Springer
Background Oxidative stress plays a key role in the etiology of male infertility. Significant
alterations in the sperm proteome are associated with poor semen quality. The aim of the …

Comparative proteomic network signatures in seminal plasma of infertile men as a function of reactive oxygen species

A Agarwal, A Ayaz, L Samanta, R Sharma, M Assidi… - Clinical proteomics, 2015 - Springer
Background Reactive oxygen species (ROS) plays a major role in the pathology of male
infertility. It is an independent biomarker of sperm function. Seminal plasma is a natural …

Proteomic signatures reveal differences in stress response, antioxidant defense and proteasomal activity in fertile men with high seminal ROS levels

TR Dias, L Samanta, A Agarwal, PN Pushparaj… - International journal of …, 2019 - mdpi.com
Elevated levels of reactive oxygen species (ROS) are a major cause of male infertility.
However, some men with high seminal ROS levels are still fertile. The main objective of this …

Proteomic analysis of seminal fluid from men exhibiting oxidative stress

R Sharma, A Agarwal, G Mohanty… - Reproductive Biology …, 2013 - Springer
Background Seminal plasma serves as a natural reservoir of antioxidants. It helps to remove
excessive formation of reactive oxygen species (ROS) and consequently, reduce oxidative …

Exploring the role of oxidative stress in sperm motility: A proteomic network approach

JC Ribeiro, R Nogueira-Ferreira, F Amado… - Antioxidants & Redox …, 2022 - liebertpub.com
Significance: Infertility is a major global health problem, with nearly half of the cases being
associated with male factors. Although reactive oxygen species (ROS) are crucial for sperm …

Seminal plasma proteomic biomarkers of oxidative stress

R Cannarella, A Crafa, F Barbagallo… - International Journal of …, 2020 - mdpi.com
The prevalence of idiopathic male infertility is high, up to 75% of patients with abnormal
sperm parameters. Hence, the research of its causes is mandatory. Oxidative stress (OS) …

Proteomic analysis of sperm proteins in infertile men with high levels of reactive oxygen species

A Ayaz, A Agarwal, R Sharma, N Kothandaraman… - Andrologia, 2018 - Wiley Online Library
Oxidative stress is a significant risk factor for male infertility. A pro‐oxidant testicular
environment may alter the expression profile of functional sperm proteins and result in poor …

Proteomics, oxidative stress and male infertility

A Agarwal, D Durairajanayagam, J Halabi… - Reproductive …, 2014 - Elsevier
Oxidative stress has been established as one of the main causes of male infertility and has
been implicated in many diseases associated with infertile men. It results from high …

[HTML][HTML] Proteomic analysis of seminal plasma from infertile patients with oligoasthenoteratozoospermia due to oxidative stress and comparison with fertile volunteers

R Herwig, C Knoll, M Planyavsky, A Pourbiabany… - Fertility and sterility, 2013 - Elsevier
Objective To compare the expression protein profile of seminal plasma from infertile men
with oligoasthenoteratozoospermia (OAT) due to oxidative stress with that of healthy, fertile …