Friedreich's ataxia (FRDA) is the most common autosomal recessive hereditary ataxia in
Caucasians. Neurological symptoms dominate the clinical picture. The underlying …

Friedreich ataxia (FRDA) is an autosomal recessive progressively debilitating degenerative
disease that principally affects the nervous system and the heart. Although FRDA is …

Friedreich ataxia (FA) represents the most frequent type of inherited ataxia. Most patients
carry homozygous GAA expansions in the first intron of the frataxin gene on chromosome 9 …

Friedreich ataxia is a rare disorder characterized by an autosomal recessive pattern of
inheritance. The disease is noted for a constellation of clinical symptoms, notably loss of …

Friedreich ataxia is the most frequent hereditary ataxia, with an estimated prevalence of 3–4
cases per 100,000 individuals. This autosomal-recessive neurodegenerative disease is …

Friedreich ataxia (FRDA) is an inherited disease that is typically caused by GAA repeat
expansion within the first intron of the FXN gene coding for frataxin. This results in the …

Friedreich ataxia is an inherited, severe, progressive neuro-and cardiodegenerative
disorder for which there currently is no approved therapy. Friedreich ataxia is caused by the …

Friedreich ataxia (FRDA) is the most common autosomal recessive ataxia worldwide. This
review highlights the main clinical features, pathophysiological mechanisms, and …

Childhood ataxia is characterized by impaired balance and coordination primarily because
of cerebellar dysfunction. Friedreich ataxia, a form of childhood ataxia, is the most common …

During the past 15 years, the pace of research advancement in Friedreich ataxia has been
rapid. The abnormal gene has been discovered and its gene product characterized, leading …