Mouse and human induced pluripotent stem cells (iPSCs) may represent a novel approach
for modeling diabetes. Taking this into consideration, the aim of this study was to generate …

Insulin-producing cells (IPCs) derived from human pluripotent stem cells (hPSCs) may be
useful in cell therapy and drug discovery for diabetes. Here, we examined various growth …

The successful landmark discovery of mouse and human inducible pluripotential stem cells
(iPSC's) by Takahashi and Yamanaka in 2006 and 2007 has triggered a revolution in the …

Background Induced pluripotent stem cells (iPSC) possess an enormous potential as both,
scientific and therapeutic tools. Their application in the regenerative medicine provides new …

Diabetes mellitus (DM) is a group of metabolic disorders characterized by high blood
glucose levels due to insufficient insulin secretion, insulin action, or both. The present-day …

Diabetes mellitus (DM) is one of the main causes of morbidity and mortality, with an
increasing incidence worldwide. The impact of DM on public health in developing countries …

In vitro differentiation of human induced pluripotent stem cells (iPSCs) into beta cells
represents an important cell source for diabetes research. Here, we fully characterized iPSC …

Aims/hypothesis The generation of induced pluripotent stem cells (iPSCs) provides a
promising possibility for type 1 diabetes therapy. However, the generation of insulin …

Human induced pluripotent stem (hiPS) cells have potential uses for drug discovery and cell
therapy, including generation of pancreatic β-cells for diabetes research and treatment. In …

The landmark discovery of induced pluripotent stem cells (iPSCs) by Shinya Yamanaka has
transformed regenerative biology. Previously, insights into the pathogenesis of chronic …