Accumulating evidence has suggested the involvement of oxidative stress in the
pathogenesis of Alzheimer's disease (AD). The main endogenous antioxidant, glutathione …

Significance: Glutathione (GSH) represents the most abundant and the main antioxidant in
the body with important functions in the brain related to Alzheimer's disease (AD). Recent …

Glutathione (GSH) is an important endogenous antioxidant found in millimolar
concentrations in the brain. GSH levels have been shown to decrease with aging …

The antioxidant properties of glutathione (GSH) and their relevance to oxidative stress
induced pathological states such as Alzheimer's disease is well-established. The utility of …

Oxidative stress has been associated with the onset and progression of mild cognitive
impairment (MCI) and Alzheimer disease (AD). AD and MCI brain and plasma display …

With millions of older individuals presently suffering from Alzheimer's disease (AD)
worldwide, AD is an unduly common form of dementia that exacts a heavy toll on affected …

Alzheimer's disease (AD) is characterized by progressive loss of memory and cognition. Our
laboratory and many others have shown that the AD brain is under extensive oxidative …

Oxidative stress in Alzheimer's disease (AD) is mediated, in part, by the loss of glutathione
(GSH). Previous studies show that γ-glutamyl transpeptidase (GGT)-resistant GSH analog, Ψ …

Supplementation of glutathione (GSH) levels through varying formulations or precursors has
thus far appeared to be a tenable strategy to ameliorate disease-associated oxidative stress …

Glutathione (GSH) is one of the most abundant thiol antioxidants in cells. Many chronic and
age-related diseases are associated with a decline in cellular GSH levels or impairment in …