[HTML][HTML] Angiogenic factors, bladder neuroplasticity and interstitial cystitis—new pathobiological insights
R Saban - Translational andrology and urology, 2015 - ncbi.nlm.nih.gov
Vascular endothelial growth factor (VEGF) is essential for normal embryonic development,
and maintenance of adult vascular function. Originally described as a vascular permeability …
and maintenance of adult vascular function. Originally described as a vascular permeability …
Urothelial expression of neuropilins and VEGF receptors in control and interstitial cystitis patients
R Saban, MR Saban, J Maier… - American Journal …, 2008 - journals.physiology.org
Interstitial cystitis (IC) is a chronic and painful bladder syndrome of unknown cause with no
reliable biological marker or effective therapy. Vascular endothelial growth factor (VEGF) …
reliable biological marker or effective therapy. Vascular endothelial growth factor (VEGF) …
Functional effects of blocking VEGF/VEGFR2 signaling in the rat urinary bladder in acute and chronic CYP-induced cystitis
K Tooke, B Girard, MA Vizzard - American Journal of …, 2019 - journals.physiology.org
High expression of VEGF is associated with immature angiogenesis within the urinary
bladder wall and bladder afferent nerve sensitization, leading to visceral hyperalgesia and …
bladder wall and bladder afferent nerve sensitization, leading to visceral hyperalgesia and …
Increased vascular endothelial growth factor expression in patients with bladder pain syndrome/interstitial cystitis: its association with pain severity and glomerulations
H Kiuchi, A Tsujimura, T Takao, K Yamamoto… - BJU …, 2009 - Wiley Online Library
OBJECTIVE To determine the angiogenic profiles in the bladder of patients with bladder
pain syndrome (BPS)/interstitial cystitis (IC), and to evaluate the relationship between these …
pain syndrome (BPS)/interstitial cystitis (IC), and to evaluate the relationship between these …
VEGF receptors and neuropilins are expressed in the urothelial and neuronal cells in normal mouse urinary bladder and are upregulated in inflammation
MR Saban, JM Backer, MV Backer… - American Journal …, 2008 - journals.physiology.org
Recent evidence supports a role for vascular endothelium growth factor (VEGF) signaling in
bladder inflammation. However, it is not clear what bladder cells are targeted by VEGF …
bladder inflammation. However, it is not clear what bladder cells are targeted by VEGF …
Vascular endothelial growth factor stimulates embryonic urinary bladder development in organ culture
B Burgu, LS McCarthy, V Shah, DA Long… - BJU …, 2006 - Wiley Online Library
OBJECTIVES To determine whether vascular endothelial growth factor A (VEGF) and its
receptors are expressed during bladder development in mice when capillaries are forming …
receptors are expressed during bladder development in mice when capillaries are forming …
Dysfunction of bladder urothelium and bladder urothelial cells in interstitial cystitis
E Graham, TC Chai - Current urology reports, 2006 - Springer
The human bladder urothelium (BU) and bladder urothelial cells (BUCs) play an important
role in the normal functioning of bladder including bladder storage. Current evidence in …
role in the normal functioning of bladder including bladder storage. Current evidence in …
VEGF signaling mediates bladder neuroplasticity and inflammation in response to BCG
MR Saban, CA Davis, A Avelino, F Cruz, J Maier… - BMC physiology, 2011 - Springer
Background This work tests the hypothesis that increased levels of vascular endothelial
growth factor (VEGF) observed during bladder inflammation modulates nerve plasticity …
growth factor (VEGF) observed during bladder inflammation modulates nerve plasticity …
[HTML][HTML] An experimental model of the epithelial to mesenchymal transition and pro-fibrogenesis in urothelial cells related to bladder pain syndrome/interstitial cystitis
XW Jin, QZ Wang, Y Zhao, BK Liu, X Zhang… - Translational …, 2021 - ncbi.nlm.nih.gov
Background Suitable in vitro models are needed to investigate urothelial epithelial to
mesenchymal transition (EMT) and pro-fibrogenesis phenotype in bladder pain …
mesenchymal transition (EMT) and pro-fibrogenesis phenotype in bladder pain …
Upregulation of vascular endothelial growth factor isoform VEGF-164 and receptors (VEGFR-2, Npn-1, and Npn-2) in rats with cyclophosphamide-induced cystitis
BP Cheppudira, BM Girard, SE Malley… - American Journal …, 2008 - journals.physiology.org
Regulation of the VEGF-VEGF receptor system was examined in the urinary bladder after
acute (2–48 h) and chronic (10 days) cyclophosphamide (CYP)-induced cystitis. ELISAs …
acute (2–48 h) and chronic (10 days) cyclophosphamide (CYP)-induced cystitis. ELISAs …