Baicalein triggers autophagy and inhibits the protein kinase B/mammalian target of rapamycin pathway in hepatocellular carcinoma HepG2 cells
Baicalein (BA), isolated from the Chinese medicinal herb Scutellariae radix (Huangqin in
Chinese), is a flavonoid with various pharmacological effects. Herein, we found that BA only …
Chinese), is a flavonoid with various pharmacological effects. Herein, we found that BA only …
Baicalein induces beclin 1-and extracellular signal-regulated kinase-dependent autophagy in ovarian cancer cells
Baicalein (BA), one of the major compounds isolated from the root of Scutellaria baicalensis
Gerogi, exhibits various pharmacological effects, such as anti-oxidant, anti-inflammatory …
Gerogi, exhibits various pharmacological effects, such as anti-oxidant, anti-inflammatory …
[HTML][HTML] Inhibition of autophagy amplifies baicalein-induced apoptosis in human colorectal cancer
Baicalein is a Chinese herbal compound extracted from Scutellaria baicalensis that has anti-
tumor properties. The aim of this study was to elucidate the mechanisms of action of …
tumor properties. The aim of this study was to elucidate the mechanisms of action of …
[HTML][HTML] AKT serine/threonine protein kinase modulates baicalin-triggered autophagy in human bladder cancer T24 cells
Baicalin is one of the major compounds in the traditional Chinese medicinal herb from
Scutellaria baicalensis Georgi. We investigated the molecular mechanisms of cell …
Scutellaria baicalensis Georgi. We investigated the molecular mechanisms of cell …
Baicalein induces apoptosis and autophagy via endoplasmic reticulum stress in hepatocellular carcinoma cells
Z Wang, C Jiang, W Chen, G Zhang… - BioMed research …, 2014 - Wiley Online Library
Background. Hepatocellular carcinoma (HCC) remains a disastrous disease and the
treatment for HCC is rather limited. Separation and identification of active compounds from …
treatment for HCC is rather limited. Separation and identification of active compounds from …
Baicalein induces autophagy and apoptosis through AMPK pathway in human glioma cells
B Liu, L Ding, L Zhang, S Wang, Y Wang… - The American Journal …, 2019 - World Scientific
Baicalein (BAI) is a natural flavonoid. It has been shown that BAI has anticancer effects, but
the molecular mechanism is still unclear. The aim of the current study was to confirm …
the molecular mechanism is still unclear. The aim of the current study was to confirm …
Baicalein induces apoptosis and autophagy of breast cancer cells via inhibiting PI3K/AKT pathway in vivo and vitro
W Yan, X Ma, X Zhao, S Zhang - Drug design, development and …, 2018 - Taylor & Francis
Purpose Baicalein, a widely used Chinese herbal medicine, has shown anticancer effects
on many types of human cancer cell lines. However, little is known about the underlying …
on many types of human cancer cell lines. However, little is known about the underlying …
Anticancer effects of baicalein on hepatocellular carcinoma cells
YH Zheng, LH Yin, THM Grahn, AF Ye… - Phytotherapy …, 2014 - Wiley Online Library
The therapeutic potential of baicalein against hepatoma cells was evaluated in vitro and in
vivo. In cell viability assays, baicalein showed significant cytotoxicity against the …
vivo. In cell viability assays, baicalein showed significant cytotoxicity against the …
Blocking autophagy enhances the apoptosis effect of bufalin on human hepatocellular carcinoma cells through endoplasmic reticulum stress and JNK activation
F Hu, J Han, B Zhai, X Ming, L Zhuang, Y Liu, S Pan… - Apoptosis, 2014 - Springer
Bufalin extracts are a part of traditional Chinese medicine, Chansu. In the current study, we
investigated the effect of bufalin on the proliferation of the human hepatocellular carcinoma …
investigated the effect of bufalin on the proliferation of the human hepatocellular carcinoma …
Baicalein induces autophagic cell death through AMPK/ULK1 activation and downregulation of m TORC 1 complex components in human cancer cells
P Aryal, K Kim, PH Park, S Ham, J Cho… - The FEBS …, 2014 - Wiley Online Library
Baicalein, a flavonoid and aglycon hydrolyzed from baicalin, has anticancer properties in
several human carcinomas, but its molecular mechanisms of action remain unclear. Here …
several human carcinomas, but its molecular mechanisms of action remain unclear. Here …
相关搜索
- carcinoma cells reticulum stress
- mammalian target hepg2 cells
- mammalian target protein kinase
- hepg2 cells protein kinase
- mammalian target rapamycin pathway
- hepg2 cells rapamycin pathway
- carcinoma cells blocking autophagy
- autophagy and apoptosis glioma cells
- rapamycin pathway protein kinase
- carcinoma cells apoptosis effect
- autophagy and apoptosis ampk pathway
- ampk pathway glioma cells
- carcinoma cells jnk activation
- carcinoma cells apoptosis and autophagy
- carcinoma cells anticancer effects