Portulaca oleracea L. as a Prospective Candidate Inhibitor of Hepatitis C Virus NS3 Serine Protease

S Noreen, I Hussain, MI Tariq, B Ijaz, S Iqbal… - Viral …, 2015 - liebertpub.com
Hepatitis C virus (HCV) infection is a worldwide health problem affecting about 300 million
individuals. HCV causes chronic liver disease, liver cirrhosis, hepatocellular carcinoma, and …

Suppression of hepatitis C virus by the flavonoid quercetin is mediated by inhibition of NS3 protease activity

L Bachmetov, M Gal‐Tanamy, A Shapira… - Journal of viral …, 2012 - Wiley Online Library
Phytochemicals exert antiviral activity and may play a potential therapeutic role in hepatitis C
virus (HCV) infection. In this work, we aimed to isolate NS3 inhibitors from traditional Indian …

[HTML][HTML] In-vitro antiviral activity of Solanum nigrum against Hepatitis C Virus

T Javed, UA Ashfaq, S Riaz, S Rehman, S Riazuddin - Virology Journal, 2011 - Springer
Background Hepatitis C is a major health problem causes liver cirrhosis, hepatocellular
carcinoma and death. The current treatment of standard interferon in combination with …

Evaluation of phytoconstituents and molecular docking against NS3 protease of hepatitis C virus

HR Naika, K Lingaraju… - Journal of …, 2015 - ingentaconnect.com
Hepatitis C Virus (HCV) infection is one of the major health problems in world wide. It is one
of the nonstructural protein 3 (NS3) possesses multiple enzyme for polyprotein, evident …

Antiviral compounds from traditional Chinese medicines Galla Chinese as inhibitors of HCV NS3 protease

D Duan, Z Li, H Luo, W Zhang, L Chen, X Xu - Bioorganic & medicinal …, 2004 - Elsevier
Under the guidance of bioassay, the EtOAc extract fraction of the Traditional Chinese
Medicine (TCM) Galla Chinese was found to be efficient in inhibiting the NS3 protease of …

Inhibition of hepatitis C virus replication by herbal extract: Phyllanthus amarus as potent natural source

YS Ravikumar, U Ray, M Nandhitha, A Perween… - Virus Research, 2011 - Elsevier
Hepatitis C virus infection is a major health problem worldwide. Developing effective
antiviral therapy for HCV is the need of the hour. The viral enzymes NS3 protease and NS5B …

Identification of Potential Bioactive Compounds from Aspergillus terreus against HCV NS3 Serine Protease

J Lin, LY Yang, ZD Pan - Chemistry & Biodiversity, 2023 - Wiley Online Library
This study was aimed to isolate bioactive compounds from the fermentation products of
Aspergillus terreus, which could inhibit NS3 protease of hepatitis C virus (HCV). The …

Anti-hepatitis C virus activity and synergistic effect of Nymphaea alba extracts and bioactive constituents in liver infected cells

S Rehman, UA Ashfaq, B Ijaz, S Riazuddin - Microbial pathogenesis, 2018 - Elsevier
Background Without an effective vaccine, hepatitis C virus (HCV) remains a global threat,
inflicting 170–300 million carriers worldwide at risk of cirrhosis and hepatocellular …

Activity of compounds from Chinese herbal medicine Rhodiola kirilowii (Regel) Maxim against HCV NS3 serine protease

G Zuo, Z Li, L Chen, X Xu - Antiviral research, 2007 - Elsevier
Treatment of the chronic hepatitis C virus (HCV) infection is an unmet medical need, and the
HCV NS3 serine protease (NS3-SP) has been used as an attractive target of antiviral …

Hepatitis C virus NS3-NS4A protease inhibitors from the endophytic Penicillium chrysogenum isolated from the red alga Liagora viscida

UW Hawas, AM El-Halawany… - … für Naturforschung C, 2013 - degruyter.com
Hepatitis C virus (HCV) NS3-NS4A protease is an attractive target for anti-HCV agents
because of its important role in replication. In this work, we demonstrated that the ethyl …