[图书][B] Characterizing targeted drug delivery and endothelial cell dynamics using in vitro blood vessel models
A Thomas - 2015 - search.proquest.com
Endothelial cells form the inner lining of blood vessels and regulate key blood vessel
functions including host defense reactions, vascular smooth muscle tone, angiogenesis, and …
functions including host defense reactions, vascular smooth muscle tone, angiogenesis, and …
[HTML][HTML] Biomimetic channel modeling local vascular dynamics of pro-inflammatory endothelial changes
A Thomas, H Daniel Ou-Yang, L Lowe-Krentz… - …, 2016 - pubs.aip.org
Endothelial cells form the inner lining of blood vessels and are exposed to various factors
like hemodynamic conditions (shear stress, laminar, and turbulent flow), biochemical signals …
like hemodynamic conditions (shear stress, laminar, and turbulent flow), biochemical signals …
Modeled vascular microenvironments: immune-endothelial cell interactions in vitro
The advancement of in vitro techniques enables a better understanding of biological
processes and improves drug screening platforms. In vitro studies allow for enhanced …
processes and improves drug screening platforms. In vitro studies allow for enhanced …
[图书][B] Endovascular transport of blood-borne molecules and their interactions with the vascular wall
HW Choi - 2008 - search.proquest.com
The pathological complications of atherosclerosis, namely heart attacks and strokes, are the
leading cause of mortality in industrialized countries. The mechanisms governing …
leading cause of mortality in industrialized countries. The mechanisms governing …
A Microfluidic Model of Microvascular Inflammation: Characterization and Testing of Endothelial-Targeted Therapeutics
These authors contributed equally to this work The microvasculature plays a key role in the
pathogenesis of sepsis, ARDS, multiorgan dysfunction, and a variety of other human …
pathogenesis of sepsis, ARDS, multiorgan dysfunction, and a variety of other human …
Leukocyte-endothelial cell interactions are linked to vascular permeability via ICAM-1-mediated signaling
R Sumagin, E Lomakina… - American Journal of …, 2008 - journals.physiology.org
Two key characteristics of the inflammatory response are the recruitment of leukocytes to
inflamed tissue as well as changes in vessel permeability. We explored the relationship …
inflamed tissue as well as changes in vessel permeability. We explored the relationship …
Differential Response of the Endothelium to Simultaneous Chemical and Mechanical Stimulation in Inflammation
RB Huang, O Eniola-Adefeso - Mechanobiology of the …, 2015 - api.taylorfrancis.com
As discussed in previous chapters, vascular-targeting via endothelial cell (EC)-expressed
molecules has potential for diagnostic and therapeutic applications in several human …
molecules has potential for diagnostic and therapeutic applications in several human …
Targeted drug delivery to endothelial adhesion molecules
VR Muzykantov - International Scholarly Research Notices, 2013 - Wiley Online Library
Endothelial cells represent important targets for therapeutic and diagnostic interventions in
many cardiovascular, pulmonary, neurological, inflammatory, and metabolic diseases …
many cardiovascular, pulmonary, neurological, inflammatory, and metabolic diseases …
Validating the Manipulation of Endothelial Cell Signaling in Vivo
JS Rudge, G Thurston - Methods in Endothelial Cell Biology, 2004 - Springer
The ultimate goal of much current research in angiogenesis and vascular biology is to
manipulate the cellular and intracellular signaling of endothelial cells, and thereby alter the …
manipulate the cellular and intracellular signaling of endothelial cells, and thereby alter the …