Towards protein-based viral mimetics for cancer therapies

U Unzueta, MV Céspedes, E Vázquez… - Trends in …, 2015 - cell.com
High resistance and recurrence rates, together with elevated drug clearance, compel the
use of maximum-tolerated drug doses in cancer therapy, resulting in high-grade toxicities …

Exploitation of viral properties for intracellular delivery

S Galdiero, A Falanga, M Vitiello… - Journal of Peptide …, 2014 - Wiley Online Library
Nanotechnology is an expanding area of study with potentially pivotal applications in a
discipline as medicine where new biomedical active molecules or strategies are …

Using viruses as nanomedicines

HE van Kan‐Davelaar, JCM Van Hest… - British journal of …, 2014 - Wiley Online Library
The field of nanomedicine involves the design and fabrication of novel nanocarriers for the
intracellular delivery of therapeutic cargo or for use in molecular diagnostics. Although …

Delivery of cancer therapies by synthetic and bio-inspired nanovectors

T Briolay, T Petithomme, M Fouet, N Nguyen-Pham… - Molecular cancer, 2021 - Springer
Background As a complement to the clinical development of new anticancer molecules,
innovations in therapeutic vectorization aim at solving issues related to tumor specificity and …

Technological advances in the use of viral and non-viral vectors for delivering genetic and non-genetic cargos for cancer therapy

DM Dogbey, VES Torres, E Fajemisin… - Drug Delivery and …, 2023 - Springer
The burden of cancer is increasing globally. Several challenges facing its mainstream
treatment approaches have formed the basis for the development of targeted delivery …

Virus-based nanocarriers for drug delivery

Y Ma, RJM Nolte, JJLM Cornelissen - Advanced drug delivery reviews, 2012 - Elsevier
New nanocarrier platforms based on natural biological building blocks offer great promises
in revolutionalizing medicine. The usage of specific protein cage structures: virus-like …

Systematic Engineering of Uniform, Highly Efficient, Targeted and Shielded Viral‐Mimetic Nanoparticles

Z Karjoo, HO McCarthy, P Patel, FS Nouri, A Hatefi - Small, 2013 - Wiley Online Library
In the past decades, numerous types of nanomedicines have been developed for the
efficient and safe delivery of nucleic acid‐based drugs for cancer therapy. Given that the …

Tailored functionalized protein nanocarriers for cancer therapy: recent developments and prospects

MAA Abdelhamid, MR Ki, AAA El-Hafeez, RG Son… - Pharmaceutics, 2023 - mdpi.com
Recently, the potential use of nanoparticles for the targeted delivery of therapeutic and
diagnostic agents has garnered increased interest. Several nanoparticle drug delivery …

Emergence in protein derived nanomedicine as anticancer therapeutics: More than a tour de force

Z Wang, K Zhi, Z Ding, Y Sun, S Li, M Li, K Pu… - Seminars in cancer …, 2021 - Elsevier
Cancer has thwarted as a major health problem affecting the global population. With an
alarming increase in the patient population suffering from diverse varieties of cancers, the …

Protein nanocarriers for targeted drug delivery for cancer therapy

MY Kariduraganavar, GB Heggannavar… - Nanocarriers for drug …, 2019 - Elsevier
This chapter describes how proteins can be used to provide effective targeted nanocarriers
for drugs to target tumors. This approach offers an exciting framework for cancer therapies in …