Objective Elevated levels of serum leptin are associated with increased adiposity and
production of pro-inflammatory cytokines. Both cytokines and body adiposity have been …

OBJECTIVE Obesity predisposes individuals to congestive heart failure (CHF) and
cardiovascular disease (CVD). Leptin regulates energy homeostasis, is elevated in obesity …

Objective To determine whether leptin is related to all-cause and cardiovascular (CV)
mortality in older adults. Patients and Methods Participants 60 years and older with plasma …

Objective At elevated concentrations, circulating leptin has been associated with metabolic
disturbances, namely insulin resistance, elevated blood pressure, inflammation, and …

Leptin levels may affect mortality through its link to inflammation and obesity. However, data
are inconclusive. This meta-analysis was performed to investigate the association of leptin …

OBJECTIVE: Leptin is an adipokine with both protective and harmful effects on the
cardiovascular (CV) system. Prior studies evaluating the association between leptin and CV …

Introduction: Leptin is an adipose tissue-derived hormone associated with cardiovascular
risk factors. We examined whether leptin predicts major adverse cardiac events (MACE) in …

Obesity has been associated with higher risk of frailty in older adults, but the
pathophysiological mechanisms are unclear. No previous study has examined the …

BACKGROUND AND AIM: Leptin, an adipocyte-derived protein, regulating food intake and
metabolism has been implicated in the development of coronary heart disease. We have …

Background Leptin is associated with cardiovascular disease (CVD); however, few studies
have assessed its relationship with metabolic syndrome, especially in an Asian population …