Making the LINC: SUN and KASH protein interactions
Cell nuclei are physically integrated with the cytoskeleton through the linker of
nucleoskeleton and cytoskeleton (LINC) complex, a structure that spans the nuclear …
nucleoskeleton and cytoskeleton (LINC) complex, a structure that spans the nuclear …
Bringing KASH under the SUN: the many faces of nucleo-cytoskeletal connections
D Razafsky, D Hodzic - Journal of Cell Biology, 2009 - rupress.org
The nucleus is the most prominent cellular organelle, and its sharp boundaries suggest the
compartmentalization of the nucleoplasm from the cytoplasm. However, the recent …
compartmentalization of the nucleoplasm from the cytoplasm. However, the recent …
[HTML][HTML] The diverse functional LINCs of the nuclear envelope to the cytoskeleton and chromatin
A Rothballer, U Kutay - Chromosoma, 2013 - Springer
The nuclear envelope (NE) is connected to the different types of cytoskeletal elements by
linker of nucleoskeleton and cytoskeleton (LINC) complexes. LINC complexes exist from …
linker of nucleoskeleton and cytoskeleton (LINC) complexes. LINC complexes exist from …
[HTML][HTML] Structural insights into SUN-KASH complexes across the nuclear envelope
Linker of the nucleoskeleton and the cytoskeleton (LINC) complexes are composed of SUN
and KASH domain-containing proteins and bridge the inner and outer membranes of the …
and KASH domain-containing proteins and bridge the inner and outer membranes of the …
Connecting the nucleus to the cytoskeleton by SUN–KASH bridges across the nuclear envelope
EC Tapley, DA Starr - Current opinion in cell biology, 2013 - Elsevier
The nuclear–cytoskeleton connection influences many aspects of cellular architecture,
including nuclear positioning, the stiffness of the global cytoskeleton, and …
including nuclear positioning, the stiffness of the global cytoskeleton, and …
[HTML][HTML] Chain reaction: LINC complexes and nuclear positioning
B Burke - F1000Research, 2019 - ncbi.nlm.nih.gov
Nuclear positioning plays an essential role in defining cell architecture and behaviour in
both development and disease, and nuclear location frequently adjusts according to internal …
both development and disease, and nuclear location frequently adjusts according to internal …
[HTML][HTML] Structural analysis of different LINC complexes reveals distinct binding modes
Linker of nucleoskeleton and cytoskeleton (LINC) complexes are molecular tethers that span
the nuclear envelope (NE) and physically connect the nucleus to the cytoskeleton. They …
the nuclear envelope (NE) and physically connect the nucleus to the cytoskeleton. They …
[HTML][HTML] LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins
BA Sosa, A Rothballer, U Kutay, TU Schwartz - Cell, 2012 - cell.com
Linker of nucleoskeleton and cytoskeleton (LINC) complexes span the nuclear envelope
and are composed of KASH and SUN proteins residing in the outer and inner nuclear …
and are composed of KASH and SUN proteins residing in the outer and inner nuclear …
A molecular model for LINC complex regulation: activation of SUN2 for KASH binding
Linkers of the nucleoskeleton and cytoskeleton are key molecular complexes that span the
nuclear envelope (NE) and provide a direct linkage between the nucleoskeleton and …
nuclear envelope (NE) and provide a direct linkage between the nucleoskeleton and …
[HTML][HTML] Differential incorporation of SUN-domain proteins into LINC complexes is coupled to gene expression
CK May, CW Carroll - PLoS One, 2018 - journals.plos.org
LInkers of Nucleoskeleton and Cytoskeleton (LINC) complexes, composed of SUN and
KASH-domain proteins, span the nuclear envelope and physically connect the nuclear …
KASH-domain proteins, span the nuclear envelope and physically connect the nuclear …