A fundamental issue in cortical processing of sensory information is whether top-down
control circuits from higher brain areas to primary sensory areas not only modulate but …

The brain transforms physical sensory stimuli into meaningful perceptions. In animals
making choices about sensory stimuli, neuronal activity in successive cortical stages reflects …

When humans perceive a sensation, their brains integrate inputs from sensory receptors and
process them based on their expectations. The mechanisms of this predictive coding in the …

Optimal behavior relies on the successful integration of complementary information from
multiple senses. The neural mechanisms underlying multisensory interactions are still poorly …

Layer (L) 2/3 pyramidal neurons in the primary somatosensory cortex (S1) are sparsely
active, spontaneously and during sensory stimulation. Long-range inputs from higher areas …

The primary somatosensory cortex (S1) is a hub for body sensation of both innocuous and
noxious signals, yet its role in somatosensation versus pain is debated. Despite known …

Primary sensory cortex discriminates incoming sensory information and generates multiple
processing streams toward other cortical areas. However, the underlying cellular …

Animals in their natural environments actively process spatiotemporally complex sensory
signals in order to guide adaptive behavior. It therefore seems likely that the properties of …

Initial anatomical and physiological studies suggested that sensory information relayed from
the periphery by the thalamus is serially processed in primary sensory cortical areas. It is …

Tactile discrimination depends on integration of information from the discrete receptive fields
(RFs) of peripheral sensory afferents. Because this information is processed over a …