The main objective of this work is to demonstrate the feasibility of using bone marrow-
derived stem cells in treating a neurodegenerative disorder such as Friedreich's ataxia. In …

Many neurodegenerative disorders share a common susceptibility to oxidative stress,
including Alzheimer's, Parkinson Disease, Huntington Disease and Friedreich's ataxia. In a …

Friedreich's ataxia (FRDA) is an incurable autosomal recessive neurodegenerative disease
caused by reduced expression of the mitochondrial protein frataxin due to an intronic GAA …

Friedreich's ataxia is an inherited neurological disorder characterised by mitochondrial
dysfunction and increased susceptibility to oxidative stress. At present, no therapy has been …

Objective Friedreich's ataxia is an incurable inherited neurological disease caused by
frataxin deficiency. Here, we report the neuroreparative effects of myeloablative allogeneic …

Friedreich's ataxia (FRDA) is a progressive neurodegenerative disorder which is, at present,
incurable. Oxidative damage and inhibition of mitochondrial function are key determinants of …

The use of regenerative medicine to treat nervous system disorders like ataxia has been
proposed to either replace or support degenerating neurons. In this study, we assessed the …

Objectives Friedreich's ataxia is a devastating neurological disease currently lacking any
proven treatment. We studied the neuroprotective effects of the cytokines, granulocyte …

Huntington's disease is an inherited neurodegenerative disorder, characterized by loss of
spiny neurons in the striatum and cortex, which usually happens in the third or fourth …

Introduction: Friedreich's ataxia (FRDA) is an autosomal recessive inherited disease that
damages nervous system and impairs muscle coordination. FRDA usually begins in …