An injectable drug-loaded hydrogel based on a supramolecular polymeric prodrug

L Xiong, Q Luo, Y Wang, X Li, Z Shen… - Chemical …, 2015 - pubs.rsc.org
We reported a novel injectable doxorubicin-loaded hydrogel based on host–guest
interaction and Schiff's base reaction. A supramolecular polymeric prodrug was prepared …

Injectable supramolecular hydrogels fabricated from PEGylated doxorubicin prodrug and α-cyclodextrin for pH-triggered drug delivery

F Li, J He, M Zhang, KC Tam, P Ni - RSC Advances, 2015 - pubs.rsc.org
Supramolecular hydrogels, which are held together by noncovalent bonds and show
responses to external stimuli, are of great interest in therapeutic delivery and tissue …

Injectable doxorubicin-loaded hydrogels based on dendron-like β-cyclodextrin–poly (ethylene glycol) conjugates

J Sheng, Y Wang, L Xiong, Q Luo, X Li, Z Shen… - Polymer …, 2017 - pubs.rsc.org
Dendron-like multifunctional β-cyclodextrin–poly (ethylene glycol)(CD–PEG) conjugates
were synthesized from amino functionalized β-cyclodextrins and poly (ethylene glycol) …

A macromolecular prodrug strategy for combinatorial drug delivery

NN Li, J Lin, D Gao, LM Zhang - Journal of colloid and interface science, 2014 - Elsevier
A novel macromolecular prodrug strategy was developed for the combinatorial delivery of
two poorly water-soluble drugs, dexamethasone and doxorubicin. In this work …

Injectable poly (ethylene glycol) hydrogels for sustained doxorubicin release

L Gao, Q Sun, Y Wang, W Zhu, X Li… - Polymers for …, 2017 - Wiley Online Library
Water‐soluble poly (ethylene glycol) derivatives with multiple “clickable” mercapto groups or
double bonds were facilely synthesized in a large scale by direct polycondensation of oligo …

Supramolecular hydrogels from cisplatin-loaded block copolymer nanoparticles and α-cyclodextrins with a stepwise delivery property

W Zhu, Y Li, L Liu, Y Chen, C Wang, F Xi - Biomacromolecules, 2010 - ACS Publications
A stepwise anticancer drug delivery system based on an injectable supramolecular hydrogel
was presented. In this system, poly (ethylene glycol)-b-poly (acrylic acid)(PEG-b-PAA) block …

A pH-sensitive and biodegradable supramolecular hydrogel constructed from a PEGylated polyphosphoester-doxorubicin prodrug and α-cyclodextrin

F Li, J He, M Zhang, P Ni - Polymer Chemistry, 2015 - pubs.rsc.org
An acid-labile and PEGylated polyphosphoester-doxorubicin prodrug (PBYP-g-PEG-g-DOX)
was prepared via a combination of ring-opening polymerization (ROP) and Cu (I)-catalyzed …

Schiff base-containing dextran nanogel as pH-sensitive drug delivery system of doxorubicin: Synthesis and characterization

H Su, W Zhang, Y Wu, X Han, G Liu… - Journal of …, 2018 - journals.sagepub.com
Stimuli-responsive hydrogels have been widely researched as carrier systems, due to their
excellent biocompatibility and responsiveness to external physiologic environment factors …

Prodrugs forming multifunctional supramolecular hydrogels for dual cancer drug delivery

W Ha, J Yu, X Song, Z Zhang, Y Liu… - Journal of Materials …, 2013 - pubs.rsc.org
Here we report a multifunctional supramolecular hydrogel based on host–guest inclusion for
loading two different anticancer drugs with different controlled release profiles. The resulting …

Supramolecular hydrogels as a universal scaffold for stepwise delivering Dox and Dox/cisplatin loaded block copolymer micelles

W Zhu, Y Li, L Liu, Y Chen, F Xi - International journal of pharmaceutics, 2012 - Elsevier
A general and simple method was presented for preparing supramolecular hydrogels to
deliver anticancer drugs. In this system, hydrophobic anticancer drug doxorubicin (Dox) was …