Antimicrobial resistance: impact on clinical and economic outcomes and the need for new antimicrobials

AK Thabit, JL Crandon, DP Nicolau - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Antimicrobial resistance is a well-recognized global threat; thus, the
development of strong infection control policies coupled with antimicrobial stewardship …

The clinical consequences of antimicrobial resistance

LB Rice - Current opinion in microbiology, 2009 - Elsevier
The continued evolution of antimicrobial resistance in the hospital and more recently in the
community threatens to seriously compromise our ability to treat serious infections. The …

The growing burden of antimicrobial resistance

PM Hawkey - Journal of antimicrobial chemotherapy, 2008 - academic.oup.com
Since the first usage of antimicrobials, the burden of resistance among bacteria has
progressively increased and has accelerated within the last 10 years. Antibiotic resistance …

Burden of antimicrobial resistance in an era of decreasing susceptibility

GS Tillotson, SH Zinner - Expert review of anti-infective therapy, 2017 - Taylor & Francis
Introduction: Antimicrobial resistance has become a global problem. Many pathogens are
becoming multidrug-resistant with the attendant increased risk of failure of standard …

Antimicrobial resistance issues of the future

WA Craig - Diagnostic microbiology and infectious disease, 1996 - Elsevier
Increasing antimicrobial resistance among respiratory pathogens has the potential to reduce
the efficacy of standard dosage regimens for many oral drugs. The goal of antimicrobial …

Antimicrobial resistance: new insights and therapeutic implications

BA Sheikh, BA Bhat, MA Mir - Applied Microbiology and Biotechnology, 2022 - Springer
Antimicrobial resistance has not been a new phenomenon. Still, the number of resistant
organisms, the geographic areas affected by emerging drug resistance, and the magnitude …

Overview: the ongoing threat of antimicrobial resistance

RR Watkins, RA Bonomo - Infectious Disease Clinics, 2020 - id.theclinics.com
The discovery and clinical implementation of antibiotics in the twentieth century is one of the
greatest achievements in modern medicine. These “miracle drugs” treat infections ranging …

Antimicrobial resistance: action to combat the rising microbial challenges

NI Paphitou - International journal of antimicrobial agents, 2013 - Elsevier
Antimicrobial therapy transformed medical practice from a merely diagnosis-focused
approach 80 years ago to a treatment-focused approach, saving millions of lives in the years …

Global antimicrobial resistance in Gram-negative pathogens and clinical need

U Theuretzbacher - Current opinion in microbiology, 2017 - Elsevier
Highlights•Carbapenem-resistant Gram-negative pathogens are a priority for R&D,
according to WHO.•Increasing need for new therapies against Klebsiella, Pseudomonas and …

Antimicrobial resistance: issues and options

J Lederberg, PF Harrison - 1998 - books.google.com
Antibiotic resistance is neither a surprising nor a new phenomenon. It is an increasingly
worrisome situation, however, because resistance is growing and accelerating while the …