An increasing number of studies have proposed a strong correlation between reactive
oxygen species (ROS)‐induced oxidative stress (OS) and the pathogenesis of Alzheimer's …

Alzheimer's disease (AD) is the most common cause of dementia and a great
socioeconomic burden in the aging society. Compelling evidence demonstrates that …

Alzheimer's disease (AD) is the most common neurodegenerative disease characterized by
the presence of senile plaques (SPs) and neurofibrillary tangles (NFTs) in the hippocampus …

The pathogenesis of Alzheimer's disease involves β amyloid (Aβ) accumulation known to
induce synaptic dysfunction and neurodegeneration. The brain's vulnerability to oxidative …

Oxidative stress is a marker of neurodegeneration and has been recently shown to be also
involved in the early stages of the pathogenesis of various neurodegenerative disorders. In …

Over the past decade, the study of oxidative stress in relation to the pathogenesis of
Alzheimer's and other neurodegenerative diseases has been transformed from an esoteric …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder affecting the elderly
population. Mechanistically, the major cause of the disease bases on the altered processing …

Alzheimer′ s disease (AD) is the most common neurodegenerative disease that causes
dementia in the elderly. Patients with AD suffer a gradual deterioration of memory and other …

Highlights•Oxidative stress is an etiopathogenic event upstream to Aβ-plaques and
neurofibrillary tangles leading to Alzheimer's disease.•Unquenched ROS perturb the …

Multiple lines of evidence demonstrate that oxidative stress is an early event in Alzheimer's
disease (AD), occurring prior to cytopathology, and therefore may play a key pathogenic role …