Abstract Interleukin-6 (IL-6) is a pro-inflammatory cytokine involved in the pathogenesis of
various autoimmune and chronic inflammatory diseases. Binding of IL-6 to its receptor (IL …

Cytokines are soluble mediators, which aid cell-to-cell communication in immune
responses, and interleukin-6 (IL-6) is a prototypical cytokine featuring redundant and …

Abstract Interleukin-6 (IL-6) is a pleiotropic cytokine with significant functions in the
regulation of the immune system. As a potent pro-inflammatory cytokine, IL-6 plays a pivotal …

Cytokines are essential modulators of the immune response. In the last decade there has
been a number of cytokines considered targets for the development of biological therapies …

Interleukin (IL)-6 cDNA was originally cloned as a terminal B cell differentiation factor into
antibody-producing plasma cells. This revealed that it is a multifunctional cytokine that acts …

Abstract Interleukin (IL)-6 is a pleiotropic cytokine that has important roles in the regulation of
the immune response, inflammation, and hematopoiesis. Disruption of IL-6 regulation might …

Interleukin-6 (IL-6) is a cytokine that plays a prominent role in the coordinated systemic host
defense response to injury. It regulates adaptation of different organ systems and …

Abstract Interleukin (IL)-6, a cytokine featuring redundancy and pleiotropic activity,
contributes to host defense against acute environmental stress, while dysregulated …

Interleukin-6 (IL-6) is a multifunctional cytokine which acts on a widevariety of cells,
regulating immune response, acute phase reaction and hematopoiesis. In accordance with …

IL-4 and IL-10 are both produced by activated TH2 cells as well as basophil/mast cells. In
addition, IL-10 is secreted by activated B cells, monocytes/macrophages and keratinocytes …