miR-185 plays an anti-hypertrophic role in the heart via multiple targets in the calcium-signaling pathways
JO Kim, DW Song, EJ Kwon, SE Hong, HK Song… - PLoS …, 2015 - journals.plos.org
MicroRNA (miRNA) is an endogenous non-coding RNA species that either inhibits RNA
translation or promotes degradation of target mRNAs. miRNAs often regulate cellular …
translation or promotes degradation of target mRNAs. miRNAs often regulate cellular …
miR-218 involvement in cardiomyocyte hypertrophy is likely through targeting REST
JJ Liu, CM Zhao, ZG Li, YM Wang, W Miao… - International Journal of …, 2016 - mdpi.com
MicroRNAs (miRNAs) have been identified as key players in cardiomyocyte hypertrophy,
which is associated with significant risks of heart failure. However, many microRNAs are still …
which is associated with significant risks of heart failure. However, many microRNAs are still …
MicroRNA-30b-5p is involved in the regulation of cardiac hypertrophy by targeting CaMKIIδ
Background MicroRNAs (miRNAs) participate in the regulation of cardiac hypertrophy.
However, it remains largely unknown as to how miRNAs are integrated into the hypertrophic …
However, it remains largely unknown as to how miRNAs are integrated into the hypertrophic …
MicroRNAs play an essential role in the development of cardiac hypertrophy
D Sayed, C Hong, IY Chen, J Lypowy… - Circulation …, 2007 - Am Heart Assoc
MicroRNAs are naturally existing, small, noncoding RNA molecules that downregulate
posttranscriptional gene expression. Their expression pattern and function in the heart …
posttranscriptional gene expression. Their expression pattern and function in the heart …
MiR-378 controls cardiac hypertrophy by combined repression of mitogen-activated protein kinase pathway factors
J Ganesan, D Ramanujam, Y Sassi, A Ahles… - Circulation, 2013 - Am Heart Assoc
Background—Several microRNAs (miRs) have been shown to regulate gene expression in
the heart, and dysregulation of their expression has been linked to cardiac disease. miR-378 …
the heart, and dysregulation of their expression has been linked to cardiac disease. miR-378 …
MicroRNAs control gene expression: importance for cardiac development and pathophysiology
D Catalucci, MVG Latronico… - Annals of the New York …, 2008 - Wiley Online Library
Growing evidence indicates that microRNAs (miRNAs) are involved in a variety of basic
biological processes, including cell proliferation, apoptosis, stress response, hematopoesis …
biological processes, including cell proliferation, apoptosis, stress response, hematopoesis …
MiRNA‐339‐5p promotes isoproterenol‐induced cardiomyocyte hypertrophy by targeting VCP to activate the mTOR signaling
X Bi, Y Zhang, Y Yu, J Yuan, S Xu, F Liu… - Cell Biology …, 2022 - Wiley Online Library
MicroRNAs (miRNAs) regulate multiple biological processes and participate in various
cardiovascular diseases. This study aims to investigate the role of miR‐339‐5p in …
cardiovascular diseases. This study aims to investigate the role of miR‐339‐5p in …
miR-222 inhibits pathological cardiac hypertrophy and heart failure
Aims Physiological cardiac hypertrophy occurs in response to exercise and can protect
against pathological stress. In contrast, pathological hypertrophy occurs in disease and often …
against pathological stress. In contrast, pathological hypertrophy occurs in disease and often …
MicroRNAs target gene and signaling pathway by bioinformatics analysis in the cardiac hypertrophy
E Shen, X Diao, C Wei, Z Wu, L Zhang, B Hu - Biochemical and biophysical …, 2010 - Elsevier
Cardiac hypertrophy is a physiological adaptive response of the heart to diverse
pathophysiological stimuli. Initially, it may be adaptive to normalize wall stress and to …
pathophysiological stimuli. Initially, it may be adaptive to normalize wall stress and to …
MiR‐221 promotes cardiac hypertrophy in vitro through the modulation of p27 expression
C Wang, S Wang, P Zhao, X Wang… - Journal of cellular …, 2012 - Wiley Online Library
Cardiac hypertrophy has been known as an independent predictor for cardiovascular
morbidity and mortality. Molecular mechanisms underlying the development of heart failure …
morbidity and mortality. Molecular mechanisms underlying the development of heart failure …