Short-term statin discontinuation increases endothelial progenitor cells without inflammatory rebound in type 2 diabetic patients

GP Fadini, M Rigato, F Boscari, R Cappellari… - Vascular …, 2015 - Elsevier
Abstract Type 2 diabetes (T2D) is characterized by impaired vascular regeneration owing to
reduced endothelial progenitor cells (EPCs). While statins are known to increase EPCs, the …

[HTML][HTML] Effects of pitavastatin versus atorvastatin on the peripheral endothelial progenitor cells and vascular endothelial growth factor in high-risk patients: a pilot …

LY Lin, CC Huang, JS Chen, TC Wu, HB Leu… - Cardiovascular …, 2014 - Springer
Background Circulating endothelial progenitor cells (EPCs) reflect endothelial repair
capacity and may be a significant marker for the clinical outcomes of cardiovascular disease …

The effect of statins on circulating endothelial progenitor cells in humans: a systematic review

B Hibbert, T Simard, FD Ramirez… - Journal of …, 2013 - journals.lww.com
Numerous clinical trials have demonstrated early reductions in cardiovascular events
occurring independently of the lipid-lowering effects of statins. These pleiotropic effects have …

Endothelial progenitor cells in diabetic patients with myocardial infarction–Can statins improve their function?

N António, A Soares, R Fernandes, F Soares… - European journal of …, 2014 - Elsevier
The effect of statins on endothelial progenitor cells (EPCs) function derived from diabetic
patients (DMpts) with acute myocardial infarction (AMI) is unknown. In this study we assess …

Effects of statins on endothelium and endothelial progenitor cell recruitment

DH Walter, S Dimmeler… - Seminars in Vascular …, 2004 - thieme-connect.com
Statins appear to be potent drugs with a variety of pleiotropic effects with vasculoprotective
and cardioprotective activity. The beneficial effects of statins on endothelial cells as well as …

Beneficial effects of statins on endothelial progenitor cells

Y Liu, J Wei, L Hu, S Hu - The American journal of the medical sciences, 2012 - Elsevier
In recent years, endothelial progenitor cells (EPCs) have been demonstrated to play an
important role during tissue vascularization and endothelium homeostasis in adults. In …

Effects of statins on endothelium and their contribution to neovascularization by mobilization of endothelial progenitor cells

DH Walter, AM Zeiher, S Dimmeler - Coronary artery disease, 2004 - journals.lww.com
Statins are potent drugs with a variety of cardiovascular protective effects which appear to
occur independent of cholesterol reduction. The vasculoprotective effects of statins might be …

Increase in circulating endothelial progenitor cells by statin therapy in patients with stable coronary artery disease

M Vasa, S Fichtlscherer, K Adler, A Aicher, H Martin… - Circulation, 2001 - Am Heart Assoc
Background—Therapeutic neovascularization may constitute an important strategy to
salvage tissue from critical ischemia. Circulating bone marrow–derived endothelial …

The impact of statins on biological characteristics of stem cells provides a novel explanation for their pleiotropic beneficial and adverse clinical effects

R Izadpanah, DJ Schächtele… - … of Physiology-Cell …, 2015 - journals.physiology.org
Statins reduce atherosclerotic events and cardiovascular mortality. Their side effects include
memory loss, myopathy, cataract formation, and increased risk of diabetes. As …

The role of endothelial progenitor cells and statins in endothelial function: a review

JF Gomez-Cerezo, B Pagan-Munoz… - … Agents in Medicinal …, 2007 - ingentaconnect.com
Endothelial dysfunction, a well recognized marker of cardiovascular risk, is an early event in
artheriosclerosis process. Diabetes mellitus, hypertension and dyslipidemia, known risk …