Unravelling the complexity and functions of MTA coregulators in human cancer

DQ Li, R Kumar - Advances in cancer research, 2015 - Elsevier
Since the initial recognition of the metastasis-associated protein 1 (MTA1) as a metastasis-
relevant gene approximately 20 years ago, our appreciation for the complex role of the MTA …

Role of MTA1 in cancer progression and metastasis

N Sen, B Gui, R Kumar - Cancer and Metastasis Reviews, 2014 - Springer
The MTA1 protein contributes to the process of cancer progression and metastasis through
multiple genes and protein targets and interacting proteins with roles in transformation …

Clinical implications of MTA proteins in human cancer

E Kaur, S Gupta, S Dutt - Cancer and Metastasis Reviews, 2014 - Springer
Metastasis-associated gene or metastasis tumor antigen 1 (MTA1) is a new member of
cancer progression-related gene family. It was first identified in rat mammary …

Physiological functions of MTA family of proteins

N Sen, B Gui, R Kumar - Cancer and Metastasis Reviews, 2014 - Springer
Although the functional significance of the metastasic tumor antigen (MTA) family of
chromatin remodeling proteins in the pathobiology of cancer is fairly well recognized, the …

The role of the MTA family and their encoded proteins in human cancers: molecular functions and clinical implications

Y Toh, GL Nicolson - Clinical & experimental metastasis, 2009 - Springer
MTA (metastasis-associated gene) is a newly discovered family of cancer progression-
related genes and their encoded products. MTA1, the first gene found in this family, has …

Emerging roles of MTA family members in human cancers

R Kumar, RA Wang, R Bagheri-Yarmand - Seminars in oncology, 2003 - Elsevier
Metastasis-associated genes (MTAs) represent a rapidly growing novel gene family. At
present, there are three different known genes (MTA1, MTA2, and MTA3) and six reported …

Properties and clinical relevance of MTA1 protein in human cancer

Y Toh, GL Nicolson - Cancer and Metastasis Reviews, 2014 - Springer
Among the genes that were found to be abundantly overexpressed in highly metastatic rat
cell lines compared to poorly metastatic cell lines, we identified a completely novel …

The many faces of MTA3 protein in normal development and cancers

L Ma, Z Yao, W Deng, D Zhang… - Current Protein and …, 2016 - ingentaconnect.com
As a family of chromatin remodeling proteins, metastasis-associated proteins (MTAs) have
shown to be the master regulators in both physiological and pathological contexts. Although …

Functions and clinical relevance of MTA proteins in human cancer. Preface.

R Kumar - Cancer Metastasis Reviews, 2014 - europepmc.org
The development, progression and metastasis of cancer is a multifactorial and polygenic
cellular process involving coordinated interplays of regulatory gene products with roles in …

[HTML][HTML] The subcellular distribution and function of MTA1 in cancer differentiation

J Liu, D Xu, H Wang, Y Zhang, Y Chang, J Zhang… - Oncotarget, 2014 - ncbi.nlm.nih.gov
The functions and mechanisms of metastasis-associated protein 1 (MTA1) in cancer
progression are still unclear due to a lagged recognition of the subcellular localization. In the …